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Microscopic polyangiitis is an uncommon systemic vasculitis of varying severity that is associated with myeloperoxidase (MPO) and perinuclear antineutrophil cytoplasmic (p-ANCA) antibodies. The most commonly affected organs are the lungs and kidneys.
Justin M. Segraves, M.D. +1 more
doaj +1 more source
Pathologic manifestations of levamisole-adulterated cocaine exposure. [PDF]
UnlabelledRheumatic manifestations of cocaine have been well described, but more recently, a dramatic increase in the levamisole-adulterated cocaine supply in the United States has disclosed unique pathologic consequences that are distinct from pure ...
Jen, Kuang-Yu, Nolan, Amber L
core +1 more source
Background The data from cohorts of childhood-onset granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) remain scarce and heterogeneous. We aimed to analyse the features at presentation, therapeutic approaches and the disease course
Michele Iudici +5 more
doaj +1 more source
Clinic manifestations in granulomatosis with polyangiitis [PDF]
Granulomatosis with polyangiitis (GPA), formerly Wegener's granulomatosis (WG), is an uncommon immunologically mediated systemic small-vessel vasculitis that is pathologically characterised by an inflammatory reaction pattern (necrosis, granulomatous ...
De Vincentiis, Marco +7 more
core +1 more source
BackgroundAntineutrophil cytoplasmic antibody-associated vasculitis is triggered by environmental factors, including silica dust exposure. Repeated tsunami waves brought a large volume of silica-containing sludge inland after the Great East Japan ...
Yoichi Takeuchi +7 more
doaj +1 more source
Hearing Loss and Kidney Dysfunction: Finding a Unifying Diagnosis
Microscopic polyangiitis (MPA) is a systemic vasculitis that affects small caliber vessels, with renal and lung compromise. Diagnosis can be challenging; timely diagnosis and treatment are important to prevent devastating complication, particularly renal
Praveena Iruku +4 more
doaj +1 more source
Unexplained deep vein thrombosis may justify screening for antineutrophil cytoplasmic antibody‐associated vasculitis as it can be an unusual presentation of this disease.
Mouna Jerbi +6 more
doaj +1 more source
ANCA-associated vasculitis [PDF]
The vasculitides are a heterogeneous group of conditions typified by their ability to cause vessel inflammation with or without necrosis. They present with a wide variety of signs and symptoms and, if left untreated, carry a significant burden of ...
Watts, Richard, Yates, Max
core +1 more source
Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad +6 more
core +2 more sources
International guidelines for the management ofANCA-associated systemic vasculitides
The paper deals with international guidelines for the management of antineutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitides (SVs) that are a group of severe life-threatening immune-mediated diseases. This group includes granulomatosis
T. V. Beketova
doaj +1 more source

