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Treatment Approaches to Granulomatosis with Polyangiitis and Microscopic Polyangiitis
We have made significant headway in our ability to induce and maintain remission in patients with granulomatosis with polyangiitis and microscopic polyangiitis. With increased understanding of the pathogenesis of antineutrophilic cytoplasmic antibody-associated vasculitides (AAV), therapeutic targets have been identified and studied in clinical trials.
Alvise Berti, Divi Cornec
exaly +6 more sources
Microscopic Polyangiitis [PDF]
In 1923, Friedrich Wohlwill described two patients with a "microscopic form of periarteritis nodosa," which was distinct from the classical form. This disease, now known as microscopic polyangiitis (MPA), is a primary systemic vasculitis characterized by inflammation of the small-caliber blood vessels and the presence of circulating antineutrophil ...
Philip Seo, Sharon Chung
exaly +6 more sources
BackgroundAntineutrophil cytoplasmic antibody-associated vasculitis is triggered by environmental factors, including silica dust exposure. Repeated tsunami waves brought a large volume of silica-containing sludge inland after the Great East Japan ...
Yoichi Takeuchi +7 more
doaj +2 more sources
Asbestos and Probable Microscopic Polyangiitis [PDF]
Several inorganic dust lung diseases (pneumoconioses) are associated with autoimmune diseases. Although autoimmune serological abnormalities are common in asbestosis, clinical autoimmune/collagen vascular diseases are not commonly reported.
George S Rashed Philteos +4 more
doaj +2 more sources
A white elderly patient, with a history of hypertension, gout and type 2 diabetes mellitus was admitted with severe cough, dyspnea, marked asthenia and hematemesis.
Noel Ernesto Pedraza Alonso +11 more
doaj +3 more sources
Microscopic polyangiitis is an uncommon systemic vasculitis of varying severity that is associated with myeloperoxidase (MPO) and perinuclear antineutrophil cytoplasmic (p-ANCA) antibodies. The most commonly affected organs are the lungs and kidneys.
Justin M. Segraves, M.D. +1 more
doaj +2 more sources
Temporal Arteritis and Vision Loss in Microscopic Polyangiitis: A Case Report and Literature Review
Microscopic polyangiitis (MPA) is an idiopathic autoimmune disease characterized by systemic vasculitis. While the lungs and kidneys are the major organs affected by MPA, it is known to involve multiple organ systems throughout the body.
Alexander G. Goglia +3 more
doaj +2 more sources
Microscopic polyangiitis: an incidental finding in a patient with stroke
Microscopic polyangiitis (MPA) is a primary systemic vasculitis characterized by inflammation of small-sized vessels associated with the presence of anti-neutrophilic cytoplasmic antibodies.
Abubakar Tauseef +9 more
doaj +2 more sources
Microscopic polyangiitis presented with biopsy-confirmed pleuritis [PDF]
We describe a case of microscopic polyangiitis manifested as pleuritis confirmed by thoracoscopic biopsy. An 80-year-old man presented with a three-day history of shortness of breath and cough.
Naoto Ishimaru +5 more
doaj +2 more sources
Microscopic Polyangiitis following Silicone Exposure from Breast Implantation [PDF]
We describe a case of a patient who developed microscopic polyangiitis (MPA) in the setting of exposure to silicone after breast implantation. A 57-year-old Hispanic woman was admitted to our hospital with complaints of fever, cough, and hemoptysis.
Judy Tan +4 more
doaj +2 more sources

