Results 81 to 90 of about 599,967 (286)

Sequence‐Based Screening of Patients With Idiopathic Polyarteritis Nodosa, Granulomatosis With Polyangiitis, and Microscopic Polyangiitis for Deleterious Genetic Variants in ADA2

Arthritis & Rheumatology, 2020
Deficiency of adenosine deaminase 2 (DADA2) is a monogenic form of vasculitis that can resemble polyarteritis nodosa (PAN). This study was undertaken to identify potential disease‐causing sequence variants in ADA2 in patients with idiopathic PAN ...
O. Schnappauf, Natalia Sampaio Moura, I. Aksentijevich, M. Stoffels, A. Ombrello, P. Hoffmann, K. Barron, E. Remmers, M. Hershfield, S. Kelly, D. Cuthbertson, S. Carette, Sharon A. Chung, Lindsy J. Forbess, N. Khalidi, C. Koening, C. Langford, Carol A. McAlear, P. Monach, L. Moreland, C. Pagnoux, P. Seo, J. Springer, A. Sreih, K. Warrington, S. Ytterberg, D. Kastner, P. Grayson, P. Merkel   +28 more
semanticscholar   +1 more source

SARS-CoV-2-INDUCED MICROSCOPIC POLYANGIITIS: CLINICAL PROBLEM

Клінічна та профілактична медицина
Introduction. During the COVID-19 pandemic, the diagnosis and treatment of ANCA-associated vasculitis (AAV) have been discussed in different ways. At the same time, the authors of many foreign publications state that SARS-CoV-2 infection can be another ...
Olga O. Gutsalenko, Borys M. Fylenko, Tetyana I. Yarmola, Nataliia V. Roiko, Iryna V. Tsyganenko   +4 more
doaj   +1 more source

The Effect of Intranasal Niclosamide on Nasal Symptoms in Patients with Anti‐Neutrophil Cytoplasmic Antibody‐Associated Vasculitis

Arthritis &Rheumatology, Accepted Article.
Objective Ear, nose and throat (ENT) manifestations are common in ANCA‐associated vasculitis (AAV). There is unmet need for drugs to target these manifestations. Granuloma formation is characteristic of proteinase 3 (PR3)‐AAV. In a zebrafish model, niclosamide inhibits PR3‐induced granuloma formation.
Benjamin Lim, Wendi Qian, Francis Dowling, Alan Salama, Rona Smith   +4 more
wiley   +1 more source

A successful endovascular intervention for massive hemorrhage due to a ruptured gastric artery aneurysm in a patient with microscopic polyangiitis: A case report

Heliyon, 2023
The formation of left gastric artery aneurysms (LGAAs) is a very rare complication of microscopic polyangiitis (MPA). Hemorrhage due to ruptured LGAAs is life threatening.
Zhonghua Chen, Chuanfang Zhu, Peng Zhao, Congsheng Tang, Yue Xiong, Yihui Yu, Feng Chen   +6 more
doaj   +1 more source

Implications of Antiphospholipid and Antineutrophilic Cytoplasmic Antibodies in the Context of Postinfectious Glomerulonephritis. [PDF]

, 2017
While antineutrophil cytoplasmic antibody (ANCA) positivity has been documented in some patients with postinfectious glomerulonephritis (PIGN) and is associated with more severe disease, antiphospholipid antibodies (APA) are not known to be a common ...
Butani, Lavjay, Leifer, Daniel
core   +4 more sources

Interstitial Lung Disease in ANCA‐Associated Vasculitis: A European Multicentre Study

Arthritis &Rheumatology, Accepted Article.
Background Interstitial Lung Disease (ILD) can occur in association with ANCA‐associated Vasculitis (AAV‐ILD) or as an isolated entity with positive ANCA (ANCA‐ILD). However, data on the epidemiology and outcomes of these conditions remain limited.
Aglaia Chalkia, Marusa Kotnik, Timothy J Sadler, Spyridon Katechis, Rachel Jones, Ajay Kamath, Aladdin J Mohammad, Sara Monti, Chetan Mukhtyar, Viral Nanda, Ioannis Petrakis, Dimitrios Petras, Ashnish Sinha, Pasupathy Sivasothy, Rona Smith, Kostas Stylianou, Dimitrios Vassilopoulos, Judith Babar, David Jayne   +18 more
wiley   +1 more source

[Microscopic polyangiitis].

Ryoikibetsu shokogun shirizu, 2001
Microscopic polyangiitis is a very rare disease characterized by the lesions of arteriolae, venulae and capillaries--mainly of the kidneys and lungs, but also of other systems and organs. The elevated titer of anti-myeloperoxidase ANCA is very important immunological indicator.
K, Takeuchi, H, Hashimoto
openaire   +3 more sources

A case of microscopic polyangiitis with diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis

Apollo Medicine, 2021
Vasculitis is a rare but important cause of diffuse alveolar hemorrhage (DAH) and should be considered in the differential diagnosis of patients who develop rapidly progressive dyspnea with nonresolving alveolar opacities on thoracic imaging.
G Vikram Reddy, Harini Seshadri
doaj   +1 more source

Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink [PDF]

, 2018
Objectives We aimed to provide insights into the aetiology of granulomatosis with polyangiitis (GPA), by conducting a large case–control study using a general population-based, prospectively collected database of healthcare records.
Abhishek Abhishek, Benchimol, Benucci, Bonatti, Burn, Chung, Cooper, CPRD, Cárdenas-Roldán, Dave, de Lind van Wijngaarden, Derrett-Smith, Dhasmana, Draibe, Fiona A Pearce, Guellec, Haubitz, Herrett, Herrett, Hollowell, Issoufaly, Lewis, Lhote, Lionaki, Mahadeva, Mahid, Mahr, Maier, Matsuyama, Matthew J Grainge, Matzaraki, Mooney, Neel, NHS Digital, NHS Digital, O’Donnell, Pagnoux, Pearce, Peter C Lanyon, Peters, Popa, Reumaux, Richard A Watts, Richard B Hubbard, Scalapino, Somers, Sopori, Springate, Suppiah, Takahashi, Vaidya, Von Elm, Watts, Wilczynska   +53 more
core   +2 more sources

The Impact of Estrogen on Stromal Elements in the Proximal Airway in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
ABSTRACT Objectives Idiopathic subglottic stenosis (iSGS) is an unexplained fibrosis of the proximal airway that predominantly impacts Caucasian women. Clinically, premenopausal patients suffer from higher recurrence rates, potentially implicating ovarian hormone 17B‐estradiol (E2) in disease pathogenesis.
Emily L. Mace, Evan Clark, Edward Talatala, Maxim Litvak, Matthew A. Buendia, Yash A. Choksi, Hongmei Wu, Yueli Zhang, Alexander Hillel, Sam Collins, Quanhu Sheng, Jing Yang, Jason Park, Alexander Gelbard   +13 more
wiley   +1 more source