Results 191 to 200 of about 2,913 (260)

Blockade of FGFR1 Trafficking to the Cell Surface Results in the Partial Mistargeting of the Receptor to Peroxisomes

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Fibroblast growth factor receptor 1 (FGFR1) is co‐translationally integrated into endoplasmic reticulum (ER) membranes and undergoes N‐glycosylation at several positions. This process is essential for FGFR1 progression through the secretory pathway.
Paulina Działek   +5 more
wiley   +1 more source

Contrast Agents for Enhanced Bioimaging: A Comprehensive Review

open access: yesChemBioChem, Volume 27, Issue 13, 14 July 2026.
Contrast agents, especially those that are nanoparticle‐based, are revolutionizing bioimaging by enabling highly sensitive, specific, and early‐stage diagnosis of diseases like cancer, using clinical imaging modalities such as CT, MRI, PET, and SPECT.
Paulo Sérgio Taube   +17 more
wiley   +1 more source

Monitoring the Colonisation Dynamics of Rugulopteryx okamurae on Algal Communities in the Northwestern Mediterranean Sea

open access: yesAquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 7, July 2026.
ABSTRACT Biological invasions are a major driver of biodiversity loss, causing profound and often irreversible ecological changes. Among these invaders, the brown alga Rugulopteryx okamurae provides a striking example. Since its arrival in 2016 in Calanques National Park (Marseille, southern France), it has drastically transformed underwater landscapes
Marie Borriglione   +8 more
wiley   +1 more source

Unraveling the Bioactive Compounds and Multi‐Target Mechanisms of the Fructus Aurantii Immaturus‐Bambusae Caulis in Taeniam Herb Pair Against Chronic Gastritis: Integrating Identification of Absorbed Constituents, Targeted Network Pharmacology, and Computational Validation

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
This work systematically explored the anti‐chronic gastritis mechanism of the FAI‐BCT herb pair. UPLC‐Q‐TOF‐MS/MS was applied to identify absorbed prototypes and metabolites of FAI‐BCT in rat plasma. Combining database mining, network pharmacology, molecular docking, and molecular dynamics simulation, we screened the key bioactive components and core ...
Yinghua Ma   +4 more
wiley   +1 more source

Silencing the Signal: The Metastasis Suppressor NDRG1 Disrupts Small Extracellular Vesicle‐Mediated Crosstalk in Pancreatic Cancer

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
NDRG1 suppresses pancreatic cancer progression by disrupting small extracellular vesicle biogenesis, altering cargo composition, and inhibiting EV uptake by cancer cells—thereby impairing tumour–stroma communication and fibrotic activation. This study reveals NDRG1 as a novel regulator of extracellular vesicle dynamics and a promising therapeutic ...
Jiawei Chang   +8 more
wiley   +1 more source

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