Results 51 to 60 of about 699,968 (272)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Multiphase imaging of freezing particle suspensions by confocal microscopy

, 2017
Ice-templating is a well-established processing route for porous ceramics. Because of the structure/properties relationships, it is essential to better understand and control the solidification microstructures.
Dedovets, Dmytro, Deville, Sylvain
core   +2 more sources

Fast wavelength-tunable ultra-violet laser source for confocal Fura-2AM imaging [PDF]

, 2007
We report a novel wavelength-flexible laser source for three-dimensional ultra-violet imaging. Based on supercontinuum generation in photonic crystal fiber, the resultant broadband laser source extended from A = 331 nm into the visible region of the ...
Esposito, E., Harris, J., McConnell, G.
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

VTA monosynaptic connections by local glutamate and GABA neurons and their distinct roles in behavior

Nature Communications
The ventral tegmental area (VTA) dopamine neurons have been implicated in diverse behaviors. These VTAdopamine neurons are intermixed with neurons that co-transmit glutamate and GABA (VTAglutamate-GABA), transmit glutamate (VTAglutamate-only) or GABA ...
M. Flavia Barbano, Huiling Wang, Shiliang Zhang, Alexey V. Shevelkin, Kevin J. Yu, Christopher T. Richie, Bing Liu, Suyun Hahn, Rong Ye, Marisela Morales   +9 more
doaj   +1 more source

Application of Confocal Laser Scanning Microscopy in Biology and Medicine

Vestnik Dermatologii i Venerologii, 2017
Fluorescence confocal laser scanning microscopy and reflectance confocal laser scanning microscopy are up-to-date highend study methods. Confocal microscopy is used in cell biology and medicine.
I. A. Volkov, N. V. Frigo, L. F. Znamenskaya, O. R. Katunina   +3 more
doaj   +1 more source

Confocal microscopy of colloidal particles: towards reliable, optimum coordinates

, 2007
Over the last decade, the light microscope has become increasingly useful as a quantitative tool for studying colloidal systems. The ability to obtain particle coordinates in bulk samples from micrographs is particularly appealing.
Ares, Arndt, Ayres, Ballard, Baumgartl, Baumgartl, Besseling, Bevington, Bobroff, Bolinder, Bromley, Brujić, Brujić, Campbell, Campbell, Cao, Cheezum, Cherry, Chestnut, Cianci, Cianci, Conrad, Courtland, Cramér, Crocker, D'Agostini, de Hoog, Derks, Dibble, Dinsmore, Dinsmore, Dinsmore, Dose, Duda, Dullens, Elkins, Elliot, Elliot, Elliot, Feigelson, Gao, Gasser, Gasser, Gonzalez, Grier, Habdas, Habdas, Haw, Hecht, Hoogenboom, Isa, Kegel, Kerker, Lampton, Leunissen, Lukosz, M.C. Jenkins, Murray, Nyquist, Pedersen, Pham, Prasad, Preparata, Press, Racca, Raffel, Royall, S.U. Egelhaaf, Sanchez, Savin, Saxton, Semwogerere, Shannon, Simeonova, Simeonova, Sugii, Thomas, Thompson, van Blaaderen, van Blaaderen, van Blaaderen, van Blaaderen, Varadan, Verhaegh, Warr, Warr, Weeks, Weeks, Willert, Wilson, Yethiraj   +90 more
core   +1 more source

Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells [PDF]

, 2018
Estrogen receptor α (ERα) is expressed in tissues as diverse as brains and mammary glands. In breast cancer, ERα is a key regulator of tumor progression.
Acconcia, Acconcia, Acerbi, Adlanmerini, Alfredo Cáceres, Ambrose, Andrés M. Toscani, Arjonen, Arnal, Axelrod, Axelrod, Bacia, Bae, Barabas, Bates, Bermudez-Hernandez, Bonifacino, Bradford, Cancer Genome Atlas Network, Caswell, Cerami, Chaumet, Chung, Ciriello, Ciriello, Correia, Cosker, Cosker, Couse, Cox, Dante R. Chialvo, De Franceschi, Debnath, Degasperi, Delcroix, Dozynkiewicz, Dunn, Eirew, Federico Coluccio Leskow, Fernando D. Stefani, Gao, Gao, Ghajar, Gillespie, Gould, Graham, Grant, Han, Han, Hartley, He, Heery, Helleman, Hernández, Hines, Honerkamp-Smith, Ianina L. Violi, Jeselsohn, Johnson, Jonathon N. Lakins, Kate Thi, Kisler, La Rosa, Letoha, Levin, Li, Long, Lu, Lu, Luciano A. Masullo, Luzio, Mak, Marina Simian, Marino, Matthew G. Rubashkin, Mayor, Mayor, Małecki, McDonough, Mina J. Bissell, Moreno-Layseca, Nam, Nardone, Nicovich, Ovesný, Pedram, Pereira, Pietras, Pontiggia, Razandi, Reid, Rocío G. Sampayo, Rust, Savkur, Schindelin, Schlegel, Skliris, Solowska, Su, Sung, Takahashi, Tiwari, Totta, Totta, Upla, Valerie M. Weaver, van de Linde, Vanlandingham, Wang, Waxmonsky, William C. Hines, Yao   +111 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Multiple scattering limit in optical microscopy

, 2017
Optical microscopy offers a unique insight of biological structures with a sub-micrometer resolution and a minimum invasiveness. However, the inhomogeneities of the specimen itself can induce multiple scattering of light and optical aberrations which ...
Aubry, Alexandre, Badon, Amaury, Boccara, A. Claude, Fink, Mathias, Lerosey, Geoffroy   +4 more
core   +1 more source