Results 61 to 70 of about 416,669 (235)

Caspase-dependent apoptosis in Riboflavin Transporter Deficiency iPSCs and derived motor neurons

Cell Death Discovery
Riboflavin Transporter Deficiency (RTD) is a rare genetic, childhood-onset disease. This pathology has a relevant neurological involvement, being characterized by motor symptoms, ponto-bulbar paralysis and sensorineural deafness.
Chiara Marioli, Maurizio Muzzi, Fiorella Colasuonno, Cristian Fiorucci, Nicolò Cicolani, Stefania Petrini, Enrico Bertini, Marco Tartaglia, Claudia Compagnucci, Sandra Moreno   +9 more
doaj   +1 more source

Confocal Microscopy in Biopsy Proven Argyrosis

Case Reports in Ophthalmological Medicine, 2013
Purpose. To evaluate the confocal microscopy findings of a 46-year-old male with bilateral biopsy proven argyrosis. Materials and Methods. Besides routine ophthalmologic examination, anterior segment photography and confocal microscopy with cornea ...
Melis Palamar, Suzan Guven Yilmaz, Taner Akalin, Sait Egrilmez, Ayse Yagci   +4 more
doaj   +1 more source

Subcellular detection of PEBCA particles in macrophages: combining darkfield microscopy, confocal Raman microscopy, and ToF-SIMS analysis. [PDF]

Drug Deliv Transl Res, 2022
Vennemann A, Breitenstein D, Tallarek E, Mørch Ý, Schmid R, Wiemann M.   +5 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

A Flexible Reporter System for Direct Observation and Isolation of Cancer Stem Cells

Stem Cell Reports, 2015
Summary: Many tumors are hierarchically organized with a minority cell population that has stem-like properties and enhanced ability to initiate tumorigenesis and drive therapeutic relapse.
Binwu Tang, Asaf Raviv, Dominic Esposito, Kathleen C. Flanders, Catherine Daniel, Bao Tram Nghiem, Susan Garfield, Langston Lim, Poonam Mannan, Ana I. Robles, William I. Smith, Jr., Joshua Zimmerberg, Rea Ravin, Lalage M. Wakefield   +13 more
doaj   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Reflectance confocal microscopy of mammary Paget disease

Dermatology Practical & Conceptual, 2017
Mammary Paget disease is the intraepidermal adenocarcinoma of the nipple area which is characterized usually by a well-demarcated eczematous plaque. Reflectance confocal microscopy (RCM), is an in vivo noninvasive diagnostic tool with a high-resolution ...
Fezal Ozdemir, Bengu Gerceker Turk, Banu Yaman, Giovanni Pellacani, Necmettin Ozdemir, Isil Karaarslan, Francesca Farnetani   +6 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

CONFOCAL MICROSCOPY OF THE CORNEA

Zdravniški Vestnik, 2004
Background. Confocal microscopy is a diagnostic method used for examination of the morphological structure of the cornea in vitro as well as in vivo.Methods.
Kristina Mikek, Marko Hawlina, Brigita Drnovšek Olup, Vladimir Pfeifer   +3 more
doaj