Results 121 to 130 of about 5,197,692 (316)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A Novel Tool for Combined AFM, SEM, and Electrical Probing of Nanostructures [PDF]
BIO Web of ConferencesSchwalb Chris +7 more
doaj +1 more source
, 2006 The axial (z-) resolution of any fluorescence microscope using a single lens is limited by diffraction to >500nm. While a modest improvement by up to a factor of 2 may be achieved by mathematical deconvolution, a substantial improvement of the axial resolution requires a radical change of the physics of imaging Since the 1990s, two families of methods ...
Bewersdorf, Jörg +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Opening the third dimension to your SEM with integrated fs-laser [PDF]
BIO Web of ConferencesVertsanova Olena +3 more
doaj +1 more source
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
Nature Methods, 2006 Michael J Rust, M. Bates, X. Zhuang
semanticscholar +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Applied MicroscopyThe non-sticky spiral silk, which typically serves as a temporary structural component in most orb-weaving spiders, functions as a permanent scaffold in the golden orb-web spider (Trichonephila clavata).
Seung-Min Lee, Myung-Jin Moon
doaj +1 more source