Results 71 to 80 of about 2,430,479 (305)

Junctional microstructure of the non-sticky spiral scaffold in the golden orb web spider, Trichonephila clavata

Applied Microscopy
The non-sticky spiral silk, which typically serves as a temporary structural component in most orb-weaving spiders, functions as a permanent scaffold in the golden orb-web spider (Trichonephila clavata).
Seung-Min Lee, Myung-Jin Moon
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Material analysis on semi-permanent makeup needles

Applied Microscopy
The cosmetic-tattoo industry is evolving every year and the microstructures of the equipment have the great potential for semi-permanent makeup applications. Present paper explores the materials and microparticles of semi-permanent makeup tattoo needles.
Hyun Sook Jin, Seung Hyun Oh, Byung Soo Chang   +2 more
doaj   +1 more source

The autophagy research in electron microscopy

Applied Microscopy, 2019
Autophagy, a highly conserved process of eukaryotic cellular recycling, plays an important role in cell survival and maintenance. Dysfunctional autophagy contributes to the pathologies of many human diseases.
Minkyo Jung, Hyosun Choi, Ji Young Mun
doaj   +1 more source

Microstructure imaging with diffusion MRI and microscopy

, 2021
Diffusion MRI is a powerful, non-invasive tool for microstructure imaging because of its sensitivity to structures on the microscopic scale. By analysing the diffusion signal we can infer the structural connectivity of the human brain or changes in the ...
Howard, Amy
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Research reviews on myosin head interactions with F-actin

Applied Microscopy
The sliding filament theory and the cross-bridge model have been fundamental in understanding muscle contraction. While the cross-bridge model explains the interaction between a single myosin head and actin filament, the native myosin molecule consists ...
Yoon Ho Park, Gang San Song, Hyun Suk Jung   +2 more
doaj   +1 more source

High-resolution low-dose scanning transmission electron microscopy

, 2010
During the past two decades instrumentation in scanning transmission electron microscopy (STEM) has pushed toward higher intensity electron probes to increase the signal-to-noise ratio of recorded images.
Stahlberg, Henning, Gipson, Bryant, Ramasse, Quentin, Buban, James P., Browning, Nigel D.   +4 more
core   +1 more source

ImageJ for Microscopy

BioTechniques, 2007
ImageJ is an essential tool for us that fulfills most of our routine image processing and analysis requirements. The near-comprehensive range of import filters that allow easy access to image and meta-data, a broad suite processing and analysis routine, and enthusiastic support from a friendly mailing list are invaluable for all microscopy labs and ...
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source