Results 91 to 100 of about 50,037 (190)

Heterocyclic phytometabolites formononetin and arbutin prevent in vitro oxidative and alkylation-induced mutagenicity

Toxicology Reports
Phenolic phytometabolites are promising bioactive compounds for management of genomic instability related diseases. Formononetin (FMN) and arbutin (ARB) are found in several plant sources.
Lizandra Vitoria de Souza Santos, Barbara Verena Dias Galvão, Lays Souza, Andreia da Silva Fernandes, Carlos Fernando Araujo-Lima, Israel Felzenszwalb   +5 more
doaj  

Structure confirmation, reactivity, bacterial mutagenicity and quantification of 2,2,4-tribromo-5-hydroxycyclopent-4-ene-1,3-dione in drinking water. [PDF]

Commun Chem
Ciccarelli D, Lancaster BMJ, Braddock DC, Calvaresi M, Mišík M, Knasmüller S, Mattioli EJ, Zerbetto F, White AJP, Marczylo T, Gant TW, Barron LP.   +11 more
europepmc   +1 more source

A novel system to determine activity of individual uridine 5'-diphospho-glucuronosyltransferase (UGT) isoforms: Recombinant UGT-beads. [PDF]

J Biol Chem
Wang T, Taub ME, Chan TS.
europepmc   +1 more source

The effects of CYP2B6 inactivators on the metabolism of ciprofol. [PDF]

PLoS One
Lu M, Zhang X, Li W, Li X, Li S, Yin X, Zhang Z.   +6 more
europepmc   +1 more source

Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility. [PDF]

J Med Chem
Romero A, Ashcraft L, Chandra A, DiMassa V, Cremin P, Collibee SE, Chuang C, Hartman J, Hwee DT, St Jean D, Malinowski J, DeBenedetto M, Moebius D, Payette J, Vargas R, Yeoman J, Motani A, Reagan J, Malik FI, Morgan BP.   +19 more
europepmc   +1 more source

Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains. [PDF]

ACS Med Chem Lett
Klope MT, Tapia Cardona JA, Chen J, Gonciarz RL, Cheng K, Jaishankar P, Kim J, Legac J, Rosenthal PJ, Renslo AR.   +9 more
europepmc   +1 more source

In Vitro Metabolism and p53 Activation of Genotoxic Chemicals: Abiotic CYP Enzyme vs Liver Microsomes. [PDF]

Chem Res Toxicol
Henneberger L, Huchthausen J, Braasch J, König M, Escher BI.   +4 more
europepmc   +1 more source

A cell fractionation and quantitative proteomics pipeline to enable functional analyses of cotton fiber development. [PDF]

Plant J
Lee Y, Rani H, Mallery EL, Szymanski DB.
europepmc   +1 more source

Design, synthesis, and biological evaluation of 2,4-dimorpholinopyrimidine-5-carbonitrile derivatives as orally bioavailable PI3K inhibitors. [PDF]

Front Pharmacol
Huang D, Yang J, Zhang Q, Zhou X, Wang Y, Shang Z, Li J, Zhang B.   +7 more
europepmc   +1 more source

Medium-vessel vasculitis following COVID-19 moderna (mRNA-1273) vaccination and the utility of PET-CT as a diagnostic tool: a case report. [PDF]

EJNMMI Rep
Cherk MH, Zolio L, Khan S, Brady S.
europepmc   +1 more source