A Rapid and Sensitive Method for the Measurement of Biological Oxidation of an Aromatic Hydrocarbon Catalyzed by Liver Microsomes. [PDF]
Robert Nilsson+8 more
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In Vitro Metabolism and p53 Activation of Genotoxic Chemicals: Abiotic CYP Enzyme vs Liver Microsomes. [PDF]
Henneberger L+4 more
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ABSTRACT Background Advanced liver fibrosis (ALF) predicts an adverse prognosis in chronic liver disease. In addition to etiological treatment, a new approach to stop or reverse residual fibrosis is desirable. Objective To assess the efficacy and safety of prolonged‐release pirfenidone (PR‐PFD) versus placebo in compensated cirrhosis.
Linda E. Muñoz‐Espinosa+17 more
wiley +1 more source
The effect of phenobarbitone on the incorporation of delta-aminolaevulinic acid into rat liver microsomes [PDF]
R. Colin Garner, A.E.M. McLean
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Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains. [PDF]
Klope MT+9 more
europepmc +1 more source
Divergent Genetic Pathways Underlying Convergent Parasitic Behaviours in Blowflies
ABSTRACT Blowfly (Diptera: Calliphoridae) exhibit diverse feeding strategies, with most species developing on decomposing organic matter. However, parasitism has evolved within the family, and some species convergently gained the ability to explore the tissues of living vertebrate hosts, which imposes critical veterinary, medical, and agricultural ...
Gisele Antoniazzi Cardoso+5 more
wiley +1 more source
Design, synthesis, and biological evaluation of 2,4-dimorpholinopyrimidine-5-carbonitrile derivatives as orally bioavailable PI3K inhibitors. [PDF]
Huang D+7 more
europepmc +1 more source
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata+6 more
wiley +1 more source
A cell fractionation and quantitative proteomics pipeline to enable functional analyses of cotton fiber development. [PDF]
Lee Y, Rani H, Mallery EL, Szymanski DB.
europepmc +1 more source