Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex [PDF]
, 2016 The group 1 metabotropic glutamate receptors 1 and 5 (mGluR1/5) have been implicated in mechanisms of synaptic plasticity and may serve as potential therapeutic targets in autism spectrum disorders.
Houtsmuller, A.B. (Adriaan) +6 more
core +1 more source
Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation. [PDF]
, 2016 Commercial dietary supplements are marketed as a panacea for the morbidly obese seeking sustainable weight-loss. Unfortunately, many claims cited by supplements are unsupported and inadequately regulated.
Bodzin, Adam S +4 more
core +1 more source
Química Nova, 2008 This work is a literature review of PBTAs, the phenylbenzotriazoles generated from the reduction and chlorination of azo dyes. The PBTAs and the non- chlorinated PBTAs were isolated for the first time from river blue rayon organic extracts that showed ...
Fábio Kummrow +1 more
doaj +1 more source
Immunochemical analysis of antigenic properties of human stomach cancer [PDF]
, 1965 From the data presented in this communication, it might be concluded that a cancer specific substance, which can be demonstrated in gel diffusion, is present in human cancer tissue, common to various epithelial cancers of different individuals, although ...
Tai, Chiaki
core +1 more source
Effects of glycyrrhizin on the pharmacokinetics of paeoniflorin in rats and its potential mechanism
Pharmaceutical Biology, 2019 Context: Paeoniflorin is reported to possess numerous pharmacological activities. Paeoniflorin and glycyrrhizin are always used together for the treatment of disease in China clinics; however, the drug–drug interaction between glycyrrhizin and ...
Hongjuan Sun, Jingfeng Wang, Juan Lv
doaj +1 more source
Human urinary mutagenicity after wood smoke exposure during traditional temazcal use. [PDF]
, 2014 In Central America, the traditional temazcales or wood-fired steam baths, commonly used by many Native American populations, are often heated by wood fires with little ventilation, and this use results in high wood smoke exposure.
HOLLAND, Nina +8 more
core +3 more sources
Effects of psoralen on the pharmacokinetics of anastrozole in rats
Pharmaceutical Biology, 2018 Context: Psoralen and anastrozole are always used together for breast cancer patients in Chinese clinics. Objective: This study investigates the effects of psoralen on the pharmacokinetics of anastrozole in rats and its potential mechanism. Materials and
Yuzhu Zhang +4 more
doaj +1 more source
Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative
Molecules, 2017 Hispidulin is a naturally occurring flavone known to have various Central nervous system (CNS) activities. Proposed synthetic approaches to synthesizing hispidulin have proven unsatisfactory due to their low feasibility and poor overall yields.
Liang-Chieh Chen +4 more
doaj +1 more source
Iron concentrations in neurons and glial cells with estimates on ferritin concentrations
, 2019 BACKGROUND: Brain iron is an essential as well as a toxic redox active element. Physiological levels are not uniform among the different cell types. Besides the availability of quantitative methods, the knowledge about the brain iron lags behind. Thereby,
Arendt, T. +4 more
core +1 more source
The mechanisms in glucose metabolism of aging hippocampus
Ibrain, EarlyView.Cognitive decline in elders stems from the irreversible loss and functional decline of neurons, with the hippocampus being particularly susceptible to age‐related neuronal deterioration. Glucose acts as the primary fuel for the brain, and a constant provision of glucose to the hippocampus is essential for memory and cognitive functions.
Rui He +6 more
wiley +1 more source