Factors influencing the incorporation of amino acid into the protein of microsome and mitochondria preparations of rat liver and liver tumour [PDF]
, 1959 Olga Greengard, P.N. Campbell
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The Journal of Clinical Pharmacology, EarlyView.Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller +4 more
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Tissue-specific uptake and distribution of liquid crystal monomers (LCMs) in mice
Environment International, 2023 Increasing evidence indicated that liquid crystal monomers (LCMs) in liquid crystal displays can be released into the environment, and ubiquitously detected in environmental matrices and even human bodies.
Yi Kong +4 more
doaj
The breakdown of adenosine triphosphate accompanying cholic acid activation by guinea-pig liver microsomes [PDF]
, 1957 William H. Elliott
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The Journal of Clinical Pharmacology, EarlyView.Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules +4 more
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Some chemical components of mitochondria and microsomes from germinating castor beans [PDF]
, 1957 Takashi Akazawa, Harry Beevers
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Porto‐sinusoidal vascular disorder in a pediatric patient with prolidase deficiency: A case report
JPGN Reports, EarlyView.Abstract Prolidase deficiency (PD) is a rare autosomal recessive disorder affecting collagen turnover, leading to diverse clinical manifestations including dermatologic lesions, hepatosplenomegaly, and vascular anomalies. Liver involvement in PD is poorly understood, with few reported cases.
Melissa Castro +5 more
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Studies on biosynthesis of cholesterol. 8. The effect of Mg2+ and Mn2+ ions and of adenosine triphosphate on enzymic activity of microsomes in sterol biosynthesis from mevalonic acid [PDF]
, 1959 Luc E. Gosselin, G. Popják
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Hereditary hypofibrinogenemia: A rare cause of chronic liver disease
JPGN Reports, EarlyView.Abstract Hypofibrinogenemia is characterized by low levels of fibrinogen with patients commonly presenting asymptomatically. This report discusses a case of hereditary hypofibrinogenemia manifesting as chronic liver disease in a 2‐year‐old male who was evaluated for elevated liver enzymes and skin/soft tissue bleeding.
Hannah Caringal +4 more
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Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke +2 more
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