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Microsporidia

Current Biology, 2023
In this Quick guide, Thomas Whelan and Naomi Fast introduce the microsporidia: obligate intracellular parasites with the most extremely reduced genomes known in eukaryotes.
Thomas A, Whelan, Naomi M, Fast
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Origins of microsporidia

Trends in Microbiology, 1998
Microsporidia are obligate intracellular parasites that infect a wide range of eukaryotes, causing severe diseases in immunocompromised humans and losses to apiaries, fisheries and silk farms. They have often been considered to be primitive eukaryotes; however, more recent evidence suggests they are more closely related to fungi.
P J, Keeling, G I, McFadden
openaire   +2 more sources

Revisiting the phylogeny of microsporidia

International Journal for Parasitology, 2021
Canonical microsporidians are a group of obligate intracellular parasites of a wide range of hosts comprising ~1,300 species of >220 genera. Microsporidians are related to fungi, and many characterised and uncharacterized groups closely related to them have been discovered recently, filling the knowledge gaps between them.
Eunji, Park, Robert, Poulin
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Comparative Genomics of Microsporidia

2022
The microsporidia are a phylum of intracellular parasites that represent the eukaryotic cell in a state of extreme reduction, with genomes and metabolic capabilities embodying eukaryotic cells in arguably their most streamlined state. Over the past 20 years, microsporidian genomics has become a rapidly expanding field starting with sequencing of the ...
Williams, BAP, Williams, TA, Trew, J
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Immune Response to Microsporidia

2022
Microsporidia are a group of pathogens, which can pose severe risks to the immunocompromised population, such as HIV-infected individuals or organ transplant recipients. Adaptive immunity has been reported to be critical for protection, and mice depleted of T cells are unable to control these infections.
Magali M, Moretto, Imtiaz A, Khan
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Microsporidia in Pennsylvania mosquitoes

Journal of Invertebrate Pathology, 1965
Abstract Aedes canadensis (Theobald) larvae infected with a Thelohania were taken from two different localities in Pennsylvania. The pathogens were determined to be Thelohania inimica Kellen and Wills, and assigned to a new subspecies, Thelohania inimica canadensis .
W, WILLS, R, BEAUDOIN
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Insights into Microsporidia Evolution from Early Diverging Microsporidia

2022
Microsporidia have drastically modified genomes and cytology resulting from their high level of adaptation to intracytoplasmic parasitism. Their origins, which had long remained enigmatic, were placed within the line of Rozella, a primitive endoparasitic chytrid.
openaire   +2 more sources

Polyamine metabolism in the Microsporidia

Biochemical Society Transactions, 2003
Members of the phylum Microspora are all obligate intracellular parasites. Little is known concerning metabolic pathways in these parasites, some of which pose serious problems in immunocompromised patients. We investigated polyamine metabolism in the systemic pathogen Enterocytozoon cuniculi using intact pre-emergent spores, and cell-free preparations.
C J, Bacchi, N, Yarlett, L M, Weiss
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Adenovirus Masquerading as Microsporidia

The Journal of Parasitology, 1996
Enterocytozoon bieneusi is a microsporidian that causes a severe, debilitating, chronic diarrhea in some patients with the acquired immunodeficiency syndrome. Specific diagnosis of E. bieneusi currently requires an invasive biopsy procedure and time-consuming preparation of specimens for electron microscopy.
G S, Visvesvara   +5 more
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