Innate and Adaptive Immune Responses Against Microsporidia Infection in Mammals
Microsporidia are obligate intracellular and eukaryotic pathogens that can infect immunocompromised and immunocompetent mammals, including humans. Both innate and adaptive immune systems play important roles against microsporidian infection.
Yinze Han +17 more
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Background The demonstration that the recently discovered Anopheles symbiont Microsporidia MB blocks malaria transmission in Anopheles arabiensis and undergoes vertical and horizontal transmission suggests that it is a promising candidate for the ...
Godfrey Nattoh +8 more
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The microsporidian fungal pathogen Enterocytozoon bieneusi is a unicellular parasite that infects humans and various animals, including pigs. Currently, there are few data on E.
Samson Teweldeberhan Ghebremichael +26 more
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Impact of genome reduction in microsporidia
Microsporidia represent an evolutionary outlier in the tree of life and occupy the extreme edge of the eukaryotic domain with some of their biological features.
Jespersen, Nathan, +5 more
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Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions [PDF]
Background: The highly compacted 2.9-Mb genome of Encephalitozoon cuniculi placed the microsporidia in the spotlight, encoding a mere 2,000 proteins and a highly reduced suite of biochemical pathways.
Ebert, Dieter +10 more
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Strategies for maximizing ATP supply in the microsporidian Encephalitozoon cuniculi: direct binding of mitochondria to the parasitophorous vacuole and clustering of the mitochondrial porin VDAC [PDF]
Microsporidia are obligate intracellular parasites with extremely reduced genomes and a dependence on host-derived ATP. The microsporidium Encephalitozoon cuniculi proliferates within a membranous vacuole and we investigated how the ATP supply is ...
Howell, Matthew +4 more
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Cytological and molecular description of Hamiltosporidium tvaerminnensis gen. et sp. nov., a microsporidian parasite of Daphnia magna, and establishment of Hamiltosporidium magnivora comb. nov. [PDF]
We describe the new microsporidium Hamiltosporidium tvaerminnensis gen. et sp. nov. with an emphasis on its ultrastructural characteristics and phylogenetic position as inferred from the sequence data of SSU rDNA, alpha-and beta-tubulin.
Ebert, Dieter +13 more
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Annotation of microsporidia genomes.
Microsporidia are a large phylum of intracellular parasites that can infect most types of animals. Species in the Nematocida genus can infect nematodes including Caenorhabditis elegans, which has become an important model to study mechanisms of ...
Hala Tamim El Jarkass (16625309) +5 more
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Effects of the microsporidium Nosema adaliae on the multicoloured Asian lady beetle, Harmonia axyridis Bryan Ellis, Susan Bjornson Effects of two microsporidia from lady beetles on the green lacewing, Chrysoperla carnea Jackline Sirisio, Susan Bjornson ...
Papers, Contributed
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Plasma membrane-located purine nucleotide transport proteins are key components for host exploitation by microsporidian intracellular parasites [PDF]
EH and TAW acknowledge support from the Marie Curie Fellowship Programme (HTTP://cordis.europa.eu/fp7/home_en.html). ERSK, JML and TME acknowledge support from the Wellcome Trust (www.wellcome.ac.uk/).
Eva Heinz (105025) +72 more
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