Results 11 to 20 of about 315,790 (145)

The Plasmodium transmission-blocking symbiont, Microsporidia MB, is vertically transmitted through Anopheles arabiensis germline stem cells. [PDF]

PLoS Pathogens
Microsporidia MB is a promising candidate for developing a symbiont-based strategy for malaria control because it disrupts the capacity of An. arabiensis to transmit the Plasmodium parasite.
Thomas Ogao Onchuru, Edward Edmond Makhulu, Purity Cassandra Ronnie, Stancy Mandere, Fidel Gabriel Otieno, Joseph Gichuhi, Jeremy Keith Herren   +6 more
doaj   +5 more sources

First identification of Microsporidia MB in Anopheles coluzzii from Zinder City, Niger [PDF]

Parasites & Vectors
Background Malaria, a disease transmitted by Anopheles mosquitoes, is a major public health problem causing millions of deaths worldwide, mostly among children under the age of 5 years.
Lamine Mahaman Moustapha, Illiassou Mamane Sadou, Ibrahima Issa Arzika, Laminou Ibrahim Maman, Michel K. Gomgnimbou, Maurice Konkobo, Abdoulaye Diabate, Etienne Bilgo   +7 more
doaj   +5 more sources

Telomere-to-telomere genome assembly of Microsporidia sp. MB, a microsporidian symbiont of Anopheles coluzzii isolated from Burkina Faso [PDF]

BMC Genomics
Background Microsporidia sp. MB is an intracellular parasite of anopheline mosquitoes identified across the African continent. Microsporidia sp. MB infections appear to have no significant effect on mosquito fitness and can vertically transmit, whilst ...
Roland Pevsner, Julien Martinez, Deepak-Kumar Purusothaman, Beth C. Poulton, Abdelhakeem I. Adam, Ewan R.S. Parry, Saré Issiaka, Abdoulaye Diabaté, Steven P. Sinkins   +8 more
doaj   +5 more sources

Bioinformatics analysis of the Microsporidia sp. MB genome: a malaria transmission-blocking symbiont of the Anopheles arabiensis mosquito [PDF]

BMC Genomics
Background The use of microsporidia as a disease-transmission-blocking tool has garnered significant attention. Microsporidia sp. MB, known for its ability to block malaria development in mosquitoes, is an optimal candidate for supplementing malaria ...
Lilian Mbaisi Ang’ang’o, Jeremy Keith Herren, Özlem Tastan Bishop   +2 more
doaj   +5 more sources

The L1014F Kdr mutation is associated with a higher prevalence and load of the Plasmodium-blocking symbiont Microsporidia MB In Anopheles Gambiae s.l. In Benin [PDF]

BMC Microbiology
Introduction The Plasmodium transmission-blocking endosymbiont Microsporidia MB was previously identified in Anopheles gambiae s.l., but its association with the carriage of the genotypes of the L1014F kdr mutation, as well as the ecological factors ...
Arthur Sovi, Minassou Juvenal Ahouandjinou, Rock Aïkpon, Gérard S. Totongnon, Boulais Yovogan, Thomas Syme, Abdramane Dembélé, Come Zinsou Koukpo, Hermann Sagbohan, Razaki Ossè, Andil Agbo-Ola, Virgile Gnanguenon, Ulrick Toffodji, Rudy Caparros Megido, Steve Zinsou Hougbe, David Mahouton Zoungbédji, Alphonse Keller Konkon, Jackie Cook, Germain Gil Padonou, Natacha Protopopoff, Martin C. Akogbéto, Louisa A. Messenger, Constantin J. Adoha   +22 more
doaj   +6 more sources

Seasonal variation of Microsporidia MB infection in Anopheles gambiae and Anopheles coluzzii in two different geographical localities in Benin [PDF]

Malaria Journal
Background Microsporidia MB, a naturally occurring Anopheles symbiont was shown to strongly impair Plasmodium transmission without imposing deleterious fitness effects on larval development, fecundity, adult survival, and adult sex ratio, and for these ...
Genevieve Tchigossou, Michel Lontsi-Demano, Eric Tossou, Pierre-Marie Sovegnon, Romaric Akoton, Danahe Adanzounon, Camille Dossou, Massioudou Koto, Azarath Ogbon, Marie Gouété, Godfrey Nattoh, Rousseau Djouaka   +11 more
doaj   +5 more sources

Imaging the lifecycle of Microsporidia sp. MB in Anopheles coluzzii from western Burkina Faso reveals octosporogony [PDF]

mSphere
A newly discovered microsporidian, Microsporidia sp. MB (MB), was recently found to block Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes from Kenya.
Ewan R. S. Parry, Roland Pevsner, Beth C. Poulton, Deepak-Kumar Purusothaman, Abdelhakeem I. Adam, Sare Issiaka, Thomas H. Ant, Stephanie M. Rainey, Etienne Bilgo, Abdoulaye Diabaté, Steven P. Sinkins   +10 more
doaj   +6 more sources

Modelling the temporal dynamics of Microsporidia MB prevalence in Anopheles mosquitoes under environmental variability [PDF]

Scientific Reports
Releasing Microsporidia MB-positive mosquitoes is being investigated as a promising component of Integrated Vector Management (IVM) strategies for malaria control. In this study, we developed a System Dynamics model to replicate the observed interactions
Charlène N. T. Mfangnia, Matteo Pedercini, Henri E. Z. Tonnang, Jeremy K. Herren   +3 more
doaj   +3 more sources

Effect of Microsporidia MB infection on the development and fitness of Anopheles arabiensis under different diet regimes [PDF]

Parasites & Vectors
Background Microsporidia MB (MB) is a naturally occurring symbiont of Anopheles and has recently been identified as having a potential to inhibit the transmission of Plasmodium in mosquitoes.
Godfred Yaw Boanyah, Lizette L. Koekemoer, Jeremy K. Herren, Tullu Bukhari   +3 more
doaj   +4 more sources

Investigation of prevalence and phylogenetic classification of Microsporidia MB and insecticide target site insensitivity resistance mutations in Anopheles gambiae s.l. and Anopheles funestus mosquitoes from Busia, Kenya [PDF]

BMC Microbiology
Background Microsporidia MB, a Plasmodium-transmission-impairing symbiont in Anopheles arabiensis, has malaria control potential. This study assessed its prevalence and phylogeny in An. gambiae s.l. and An.
Herzel Tiffany Wandera, Godfrey Nattoh, Daniel Kiboi, Manase Onyango Aloo, Stanley Kitur, Sharon Nyagaka, Malvin Atieno Otieno, Eric Ochomo, Damaris Matoke-Muhia, Jeremy Keith Herren, Luna Kamau   +10 more
doaj   +3 more sources