Results 21 to 30 of about 249,690 (180)

Draft genome of Microsporidia sp. MB-a malaria-blocking microsporidian symbiont of the Anopheles arabiensis. [PDF]

Microbiol Resour Announc
We report the draft whole-genome assembly of Microsporidia sp. MB, a symbiotic malaria-transmission-blocking microsporidian isolated from Anopheles arabiensis in Kenya. The whole-genome sequence of Microsporidia sp. MB has a length of 5,908,979 bp, 2,335
Ang'ang'o LM, Waweru JW, Makhulu EE, Wairimu A, Otieno FG, Onchuru T, Tastan Bishop Ö, Herren JK.   +7 more
europepmc   +4 more sources

Spatial Distribution of Microsporidia MB Along Clinal Gradient and the Impact of Its Infection on Pyrethroid Resistance in Anopheles gambiae s.l. Mosquitoes from Nigeria and Niger Republic

Parasitologia
Microsporidia MB (MB), a promising biological control agent, suppresses Plasmodium falciparum transmission in Anopheles mosquitoes. This study examined the spatial distribution of MB infection in natural populations of An. gambiae s.l.
Lamine M. Moustapha, Muhammad M. Mukhtar, Abdoul-Nasser H. Sanda, Shuaibu Adamu, Yusuf Y. Aliyu, Hadizat K. Einoi, Maryam U. Maigari, Peter C. Okeke, David E. Nwele, Abiodun Obembe, Udoka C. Nwangwu, Jeremy K. Herren, Sulaiman S. Ibrahim   +12 more
doaj   +3 more sources

Mathematical modelling of the interactive dynamics of wild and Microsporidia MB-infected mosquitoes.

Mathematical biosciences and engineering : MBE, 2023
A recent discovery highlighted that mosquitoes infected with Microsporidia MB are unable to transmit the Plasmodium to humans. Microsporidia MB is a symbiont transmitted vertically and horizontally in the mosquito population, and these transmission ...
Charlène N. T. Mfangnia, Henri E. Z. Tonnang, B. Tsanou, J. Herren   +3 more
semanticscholar   +6 more sources

A Sex-Structured Mmathematical Model of Mosquito Infection with Microsporidia MB: Model Reduction and Release Strategies

International Journal of Applied and Computational Mathematics, 2023
Abstract Malaria remains a significant public health burden in Sub-Saharan African countries, hindering their development. A promising strategy to combat this disease involves the use of the bacterium Microsporidia MB to reduce/replace disease-transmitting wild mosquito population.
Dhorasso Temfack, B. Tsanou, J. Lubuma, Mouhamadou Diaby   +3 more
semanticscholar   +2 more sources

Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees. [PDF]

PLoS Pathogens, 2009
Recent steep declines in honey bee health have severely impacted the beekeeping industry, presenting new risks for agricultural commodities that depend on insect pollination.
R Scott Cornman, Yan Ping Chen, Michael C Schatz, Craig Street, Yan Zhao, Brian Desany, Michael Egholm, Stephen Hutchison, Jeffery S Pettis, W Ian Lipkin, Jay D Evans   +10 more
doaj   +5 more sources

Localisation and tissue tropism of the symbiont Microsporidia MB in the germ line and somatic tissues of Anopheles arabiensis

mBio, 2023
The Anopheles symbiont, Microsporidia MB, is maternally inherited and has a strong malaria transmission-blocking phenotype in Anopheles arabiensis. Microsporidia MB is also vertically transmitted, sexually transmitted and avirulent. These characteristics
E. E. Makhulu, T. Onchuru, Joseph Gichuhi, F. G. Otieno, A. Wairimu, Joseph N. Muthoni, Lizette Koekoemoer, J. Herren   +7 more
semanticscholar   +4 more sources

Discovery of sporogeny in the malaria transmission-blocking symbiont of Anopheles mosquitoes [PDF]

mSphere
In recent work, Parry et al. provide a detailed visualization of Microsporidia MB sporogeny (E. R. S. Parry, R. Pevsner, B. C. Poulton, D.-K. Purusothaman, et al., mSphere 10:e00851-24, 2025, https://doi.org/10.1128/msphere.00851-24).
Jeremy K. Herren
doaj   +2 more sources

Changes in the Anopheles arabiensis transcriptome and gut microbiota profiles associated with Microsporidia MB

bioRxiv
AbstractMicrosporidia MBis an endosymbiotic microbe found inAnophelesmosquito populations. This symbiont can blockPlasmodiumtransmission in mosquitoes, and it can spread through mosquito populations and be sustained over generations by vertical and horizontal transmission.
J. W. Waweru, Nicola J. Mulder, Cynthia Nyambura King’ori, Irene Muiruri, Mwatum Maloba Alakonya, E. E. Makhulu, Lilian Mbaisi Ang’ang’o, Joseph Gichuhi, Daniel K Masiga, J. Herren   +9 more
semanticscholar   +2 more sources

Fungal microbiota diversity in Aedes, Anopheles and Culex and their potential use as biological tools to control vector-borne diseases, a systematic review. [version 1; peer review: 1 approved, 2 approved with reservations] [PDF]

Wellcome Open Research
Background Mosquitoes harbor diverse and dynamic microbiota which plays a critical role in shaping their development, survival and vector competence.
Aicha Fatimata Sodré, Doubé Lucien Lamy, Abdoulaye Diabaté, Etienne Bilgo, Nouhoun Traore, Fernand Sankara   +5 more
doaj   +2 more sources

Temperature modulates the dissemination potential of Microsporidia MB, a malaria-blocking endosymbiont of Anopheles mosquitoes

bioRxiv
The endosymbiont Microsporidia MB is a promising malaria control strategy that inhibits the development of Plasmodium naturally in Anopheles mosquitoes. To be successful, it would be necessary to significantly increase the prevalence of Microsporidia MB ...
F. G. Otieno, P. Barreaux, Affognon Steeven Belvinos, E. E. Makhulu, T. Onchuru, A. Wairimu, Stancy Mandere Omboye, Cynthia Nyambura King’ori, Sokame Bonoukpoè Mawuko, Anthony Nyamache Kebira, J. Herren   +10 more
semanticscholar   +2 more sources