Results 221 to 230 of about 1,320,439 (381)

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

open access: yesAdvanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li   +17 more
wiley   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

open access: yesAdvanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai   +14 more
wiley   +1 more source

The E3 Ubiquitin Ligase, CHIP/STUB1, Inhibits Aggregation of Phosphorylated Proteoforms of Microtubule-associated Protein Tau (MAPT). [PDF]

open access: yesJ Mol Biol, 2023
Nadel CM   +7 more
europepmc   +1 more source

A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds

open access: yesAdvanced Science, EarlyView.
pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou   +7 more
wiley   +1 more source

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

open access: yesJournal of Biological Chemistry, 1986
I. Grundke‐Iqbal   +5 more
semanticscholar   +1 more source

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