Results 21 to 30 of about 189,832 (159)
Frontiers in Cell and Developmental Biology, 2023 Microtubules are filamentous structures that play a critical role in a diverse array of cellular functions including, mitosis, nuclear translocation, trafficking of organelles and cell shape.
Thomas D. Cushion +5 more
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The Evolution of Tau Phosphorylation and Interactions
Frontiers in Aging Neuroscience, 2019 Tau is a neuronal microtubule-associated protein (MAP) that is involved in the regulation of axonal microtubule assembly. However, as a protein with intrinsically disordered regions (IDRs), tau also interacts with many other partners in addition to ...
Nataliya I. Trushina +7 more
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Neuronal and Glial Distribution of Tau Protein in the Adult Rat and Monkey
Frontiers in Molecular Neuroscience, 2021 Tau is a microtubule-associated protein for which the physiological functions remain a topic of vigorous investigation. Additionally, tau is a central player in the pathogenesis of several diseases such as Alzheimer’s disease and several frontotemporal ...
Nicholas M. Kanaan +3 more
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Tau protein plays a role in the mechanism of cognitive disorders induced by anesthetic drugs
Frontiers in Neuroscience, 2023 Cognitive disorders are mental health disorders that can affect cognitive ability. Surgery and anesthesia have been proposed to increase the incidence of cognitive dysfunction, including declines in memory, learning, attention and executive function. Tau
Zheping Chen +7 more
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Microtubule-associated protein 1B [PDF]
The Journal of Cell Biology, 2001 Myelin-associated glycoprotein (MAG) is expressed in periaxonal membranes of myelinating glia where it is believed to function in glia–axon interactions by binding to a component of the axolemma. Experiments involving Western blot overlay and coimmunoprecipitation demonstrated that MAG binds to a phosphorylated neuronal isoform of microtubule ...
Rachelle Franzen +5 more
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Nature Communications, 2017 Dynein is a microtubule motor the motility of which is affected by the microtubule-associated protein She1. Here, the authors show that She1 alters dynein stepping behavior and increases its microtubule affinity through simultaneous interactions with the
Kari H. Ecklund +5 more
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Microtubule-Associated Protein 2 Expression in Canine Glioma
Frontiers in Veterinary Science, 2019 Canine glioma is considered a potential model for human glioma, with recent studies of occurrence, therapy, and reclassification supporting the value of the canine model.
Elena Alina Demeter +4 more
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Frontiers in Neurology, 2020 Tau protein (MAPT) is classified as a microtubule-associated protein (MAP) and is believed to regulate the axonal microtubule arrangement. It belongs to the tau/MAP2/MAP4 family of MAPs that have a similar microtubule binding region at their carboxy ...
Roland Brandt +4 more
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Microtubule-associated protein 1B [PDF]
The Journal of Cell Biology, 2002 Giant axonal neuropathy (GAN), an autosomal recessive disorder caused by mutations in GAN, is characterized cytopathologically by cytoskeletal abnormality. Based on its sequence, gigaxonin contains an NH2-terminal BTB domain followed by six kelch repeats, which are believed to be important for protein–protein interactions (Adams, J., R.
Jianqing Ding +6 more
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CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites. [PDF]
PLoS ONE, 2013 Integrity of the microtubule spindle apparatus and intact cell division checkpoints are essential to ensure the fidelity of distributing chromosomes into daughter cells.
Chanelle M Case +6 more
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