Results 131 to 140 of about 262,894 (312)

Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules' physical properties and neurite morphology. [PDF]

Sci Rep, 2023
Nishida K, Matsumura K, Tamura M, Nakamichi T, Shimamori K, Kuragano M, Kabir AMR, Kakugo A, Kotani S, Nishishita N, Tokuraku K.   +10 more
europepmc   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

Evaluating the Expression and Prognostic Value of Genes Encoding Microtubule-Associated Proteins in Lung Cancer. [PDF]

Int J Mol Sci, 2022
Singharajkomron N, Yodsurang V, Seephan S, Kungsukool S, Petchjorm S, Maneeganjanasing N, Promboon W, Dangwilailuck W, Pongrakhananon V.   +8 more
europepmc   +1 more source

Specific induction of the high-molecular-weight microtubule-associated protein 2 (hmw-MAP2) by betel quid extract in cultured oral keratinocytes: clinical implications in betel quid-associated oral squamous cell carcinoma (OSCC) [PDF]

, 2003
J. Y.-F. Chen
openalex   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Figure S8 from UNC-45A Is a Novel Microtubule-Associated Protein and Regulator of Paclitaxel Sensitivity in Ovarian Cancer Cells [PDF]

, 2023
Ashley Mooneyham, Yoshie Iizuka, Qing Yang, Courtney Coombes, Mark McClellan, Vijayalakshmi Shridhar, Edith Emmings, Mihir Shetty, Liqiang Chen, Teng Ai, Joyce Meints, Michael K. Lee, Melissa Gardner, Martina Bazzaro   +13 more
openalex   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

ADNP, a Microtubule Interacting Protein, Provides Neuroprotection Through End Binding Proteins and Tau: An Amplifier Effect

Frontiers in Molecular Neuroscience, 2018
Illana Gozes, Yanina Ivashko-Pachima, Carmen L. Sayas   +2 more
doaj   +1 more source

Indolyl-chalcone derivatives trigger apoptosis in cisplatin-resistant mesothelioma cells through aberrant tubulin polymerization and deregulation of microtubule-associated proteins. [PDF]

Front Oncol, 2023
Steinlein S, Essmann F, Ghilardi AF, Horn H, Schüler J, Hausser A, Sun L, Ott G, Kalla C.   +8 more
europepmc   +1 more source

Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation [PDF]

, 2019
Junhui Zhang, Lingfei Li, Qiong Zhang, Wensheng Wang, Dongxia Zhang, Jiezhi Jia, Yanling Lv, Hongping Yuan, Huapei Song, Xiang Fei, Jiongyu Hu, Yuesheng Huang   +11 more
openalex   +1 more source