PostāLECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley +1 more source
Expression of recombinant human glutamylating TTLLs in human cells leads to differential tubulin glutamylation patterns, with only TTLL6 disrupting microtubule dynamics. [PDF]
Al Kabbani MA +4 more
europepmc +1 more source
Discovery of an Atypical Arp2/3 Complex in Malaria Parasites Sheds New Light on Nuclear Actin
ABSTRACT The Arp2/3 complex is a key actin nucleator essential for cytoskeletal dynamics in eukaryotes. Previously believed absent in apicomplexan parasites, we recently identified an atypical Arp2/3 complex in malaria parasites consisting of five divergent subunits and a putative kinetochoreāassociated factor.
Franziska Hentzschel +2 more
wiley +1 more source
Architects of the Developing Brain: Cytoskeleton-Organizing Molecules in Neurodevelopmental Disorders. [PDF]
Achkasova KA +5 more
europepmc +1 more source
Structure first - exploration and discovery with cryo-electron microscopy. [PDF]
Leung MR.
europepmc +1 more source
The Chromatin Protein CFDP1 Activates TPX2 and Promotes Chromosomal Microtubule Nucleation and Spindle Assembly. [PDF]
Gopinathan G, Luan X, Diekwisch TGH.
europepmc +1 more source
Microtubule affinity-regulating kinase 4 exacerbates diabetic cardiomyopathy by inhibiting UNC-51-like kinase 1-mediated mitochondrial autophagy. [PDF]
Wu Y +6 more
europepmc +1 more source
Dissecting cytoskeletal crosstalk through reconstituted actin-microtubule systems. [PDF]
Chowdhury MAH, Kandel R, Reinemann DN.
europepmc +1 more source
The microtubule nexus linking amyloid beta and tau: A simple and unifying theory for the underlying cause of Alzheimer's disease. [PDF]
Shoff TA +3 more
europepmc +1 more source

