Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook +2 more
wiley +1 more source
Identification of a cytosol-to-nucleus feedback loop that regulates neuronal microtubule nucleation. [PDF]
Kumar N +7 more
europepmc +1 more source
The C‐Terminal Regions of TRAK Proteins Contain MIRO‐Independent Mitochondrial Localization Domains
ABSTRACT Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO‐independent MOM‐localizing domain interacts more tightly with the MOM.
Lili Mitchell +4 more
wiley +1 more source
Roles of cytoskeleton in metastasis: from its mechanism to therapeutic strategies. [PDF]
Lim S, Woo S, Lee KW, Kim KD.
europepmc +1 more source
CDK1-driven phosphorylation networks promote glioblastoma progression via MAP1B-mediated microtubule destabilization. [PDF]
Li JT +5 more
europepmc +1 more source
Golgi-Associated Protein JAKMIP2 Is Linked to the Centrosome and Performs Microtubule-Related Functions. [PDF]
Ulas E +3 more
europepmc +1 more source
Technological advances in visualizing and rewiring microtubules during plant development. [PDF]
Park S, Muroyama A.
europepmc +1 more source
Identification of locally activated spindle-associated proteins in oocytes uncovers a phosphatase-driven mechanism. [PDF]
Wan X +5 more
europepmc +1 more source
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Microtubules and microtubule-associated proteins
Current Opinion in Cell Biology, 1995Microtubule research is becoming increasingly diverse, reflecting the many isoforms and modifications of tubulin and the many proteins with which microtubules interact. Recent advances are particularly visible in four areas: microtubule motor proteins (their structures, stepping modes, and forces); microtubule nucleation (the roles of centrosomes and ...
Mandelkow, Eckhard, Mandelkow, Eva
openaire +3 more sources

