Results 261 to 270 of about 406,325 (331)

Role of GTP hydrolysis in microtubule treadmilling and assembly.

, 1981
Robert L. Margolis
openalex   +2 more sources

Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice

Annals of Neurology, EarlyView.
Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier   +19 more
wiley   +1 more source

STK405759 targets microtubules, modulates STAT1, and enhances ruxolitinib efficacy in myeloproliferative neoplasms. [PDF]

Am J Cancer Res
Rozic G, Makaros Y, Shapira-Netanelov I, Kardash T, Maizels Y, Koman I, Leiba M, Duek A.   +7 more
europepmc   +1 more source

Correction: GSK-3 Activity Is Critical for the Orientation of the Cortical Microtubules and the Dorsoventral Axis Determination in Zebrafish Embryos

, 2012
Ming Shao, Yushuang Lin, Zhongzhen Liu, Ying Zhang, Lifeng Wang, Changbin Liu, Hongwei Zhang   +6 more
openalex   +2 more sources

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Erratum: Ambroxol enhances anti-cancer effect of microtubule-stabilizing drug to lung carcinoma through blocking autophagic flux in lysosome-dependent way. [PDF]

Am J Cancer Res
Zhang X, Chen Q, Chen M, Ren X, Wang X, Qian J, Sun Y, Sha X.   +7 more
europepmc   +1 more source

The CCR4-NOT deadenylase complex mediates tubulin autoregulation <i>via</i> specific adapters CNOT10 and CNOT11. [PDF]

MicroPubl Biol
Sarbanes SL, Hogg JR, Roll-Mecak A.
europepmc   +1 more source

AI‐Assisted Customizable SERS‐Based Aptasensor for Label‐Free, Rapid, and Sensitive Detection of Tau: Comparative Analysis Using Random Forest and Convolutional Neural Networks

Analysis &Sensing, EarlyView.
A customizable SERS‐based aptasensor platform integrates aptamer‐functionalized gold nanoparticles with machine learning models (RF and CNN) to detect tau protein, a key biomarker for Alzheimer's disease. This rapid, label‐free detection system achieves a detection limit of 100 pM, enabling early diagnosis and monitoring of disease progression.
Farbod Ebrahimi, Farshad Ebrahimi, Anjali Kumari, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Synergistic effect study on the co-delivery of paclitaxel and SiRNA targeting STMN1 based on MPDA nanoparticles in the therapy of ovarian cancer. [PDF]

J Nanobiotechnology
Qian X, Yuan Y, Zhang Y, Li M, Wang X, Li W, Wen L, Duan G, Han Y.   +8 more
europepmc   +1 more source