Results 261 to 270 of about 359,607 (329)

Synthesis and Evaluation of Trehalose‐Based Mertansine Warheads for Bacillus Calmette–Guérin Delivery of Anticancer Agents

ChemBioChem, EarlyView.
Bacillus Calmette–Guérin (BCG) immunotherapy is the gold standard for nonmuscle invasive bladder cancer (NMIBC). However, it is limited by adverse effects and resistance, despite eliciting a robust immune response. This proof‐of‐concept study explores Antigen 85‐mediated, metabolically with trehalose‐PEG4 mertansine‐labeled BCG as a novel treatment ...
Michael Grimmeisen, Xuan Wang, Melissa Weldle, Kerstin Sartory, Sara Benkhelifa, Yu Zhang, Trinh Dao, Jonas Meyer, Oliver Gorka, Olaf Groß, Claudia Jessen‐Trefzer   +10 more
wiley   +1 more source

The polar code for patterning: how polarity and the cytoskeleton orchestrate asymmetric cell division during plant development. [PDF]

Front Cell Dev Biol
Garhewal A, Angres GJ, Muroyama A.
europepmc   +1 more source

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

ChemistryEurope, EarlyView.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

Polyglutamylation of microtubules drives neuronal remodeling. [PDF]

Nat Commun
Gavoci A, Zhiti A, Rusková M, Magiera MM, Wang M, Ziegler KA, Hausrat TJ, Ugwuja AI, Chakraborty S, Engelhardt S, Kneussel M, Balastik M, Janke C, Misgeld T, Brill MS.   +14 more
europepmc   +1 more source

Interaction of viomycin and aminoglycoside antibiotics with tubulin and microtubules.

, 1978
Tetsu Akiyama, Kenji Tanaka, Nobuo Tanaka, Yoshiaki Nonomura   +3 more
openalex   +2 more sources

Decoding the role of microtubules: a trafficking road for vesicle. [PDF]

Theranostics
Qu J, Li J, Wang H, Lan J, Huo Z, Li X.
europepmc   +1 more source

Microtubules and protein secretion in rat lacrimal glands. Inhibitory effect of the tubulin . colchicine complex isolated from lacrimal glands upon brain tubulin polymerization. Identification of the complex by gel electrophoresis.

, 1979
Anne‐Marie Chambaut‐Guérin, P. Müller, B. Rossignol   +2 more
openalex   +1 more source

TRiC Is a Structural Component of Mammalian Sperm Axonemes

Cytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown, Miguel Ricardo Leung, Tzviya Zeev‐Ben‐Mordehai, Rui Zhang   +3 more
wiley   +1 more source

Vasohibins in Health and Disease: From Angiogenesis to Tumorigenesis, Multiorgan Dysfunction, and Brain-Heart Remodeling. [PDF]

Cells
Abbas G, Kirabo A, Ahmed U, Liu J, Chen J.   +4 more
europepmc   +1 more source

Some Aspects on the Organization of Microfilaments and Microtubules in Relation to Nondisjunction

, 1979
Agneta Önfelt, Claes Ramel
openalex   +1 more source