Results 261 to 270 of about 407,687 (331)

New progress on the role and mechanism of tau protein in Alzheimer's disease and depression. [PDF]

Front Neurol
Wang Y, Zhou J, Zhou Q, Wang H.
europepmc   +1 more source

Enhancing high-content imaging for studying microtubule networks at large-scale. [PDF]

, 2019
Hao-Chih Lee, Sarah T. Cherng, Riccardo Miotto, Joel T. Dudley   +3 more
openalex  

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Luminal acetylation of microtubules is not essential for <i>Plasmodium berghei</i> and <i>Toxoplasma gondii</i> survival. [PDF]

Microb Cell
Kumar T, Röver K, Stortz JF, Binder AM, Spreng B, Konert M, Meissner M, Frischknecht F, Jimenez-Ruiz E.   +8 more
europepmc   +1 more source

AI‐Assisted Customizable SERS‐Based Aptasensor for Label‐Free, Rapid, and Sensitive Detection of Tau: Comparative Analysis Using Random Forest and Convolutional Neural Networks

Analysis &Sensing, EarlyView.
A customizable SERS‐based aptasensor platform integrates aptamer‐functionalized gold nanoparticles with machine learning models (RF and CNN) to detect tau protein, a key biomarker for Alzheimer's disease. This rapid, label‐free detection system achieves a detection limit of 100 pM, enabling early diagnosis and monitoring of disease progression.
Farbod Ebrahimi, Farshad Ebrahimi, Anjali Kumari, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Morphometric analysis of postnatal lung development in the gray short‐tailed opossum (Monodelphis domestica): An ultrastructural study

The Anatomical Record, EarlyView.
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley   +1 more source

Lipoxin A4 improves myocardial ischemia/reperfusion injury through the Notch1-Nrf2 signaling pathway. [PDF]

Open Life Sci
Yan X, Chen A, Gong Y, Xu J, Lu J, Wang L, Fan Y, Gao N, Zhou L, Cao H, Kuang X.   +10 more
europepmc   +1 more source

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

Animal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li, Yanyan Sun, Jingwei Yuan, Xiangchen Li, Lei Shi, Adamu Mani Isa, Yuanmei Wang, Pingzhuang Ge, Yunhe Zong, Panlin Wang, Jilan Chen   +10 more
wiley   +1 more source

KDM4A serves as an α-tubulin demethylase regulating microtubule polymerization and cell mitosis. [PDF]

Sci Adv
Cao S, Wang S, Xie X, Tan X, Hu X, Shao F, Liu Y, Zhang X, Cheng H, Diao L, Bao L.   +10 more
europepmc   +1 more source

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source