Results 271 to 280 of about 199,967 (323)

The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability

Cytoskeleton, EarlyView.
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou, Maria C. Burns, Aynsley McDermott, Karolina Jaworek, Stacey J. Scott, James G. Wakefield, Lori Borgal   +6 more
wiley   +1 more source

Brief biology and pathophysiology of Tekt bundles. [PDF]

Cell Adh Migr
Yin J, Liu M, Wang X, Miao H, He W, Liu W, Yu Z, Zhang Q, Bai J, Cheng Y, Ni B.   +10 more
europepmc   +1 more source

Microtubule MAPping

Cell, 1990
openaire   +2 more sources

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

Correction to Supporting Information for Utzschneider et al., Force balance of opposing diffusive motors generates polarity-sorted microtubule patterns. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons. [PDF]

Elife
Costa AC, Murillo BR, Bessa R, Ribeiro R, Ferreira da Silva T, Porfírio-Rodrigues P, Martins GG, Brites P, Kneussel M, Misgeld T, Brill MS, Sousa MM.   +11 more
europepmc   +1 more source

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

Cytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah, Franz Meitinger, Midori Ohta   +2 more
wiley   +1 more source

Insights into the role of phosphorylation on microtubule cross-linking by PRC1. [PDF]

Mol Biol Cell
Tai E, Henglein A, Alfieri A, Saxena G, Forth S.   +4 more
europepmc   +1 more source

Active microtubule-actin cross-talk mediated by a nesprin-2G-kinesin complex. [PDF]

Sci Adv
Sahabandu N, Okada K, Khan A, Elnatan D, Starr DA, Ori-McKenney KM, Luxton GW, McKenney RJ.   +7 more
europepmc   +1 more source

β‐Glucuronidase‐Responsive Albumin‐Binding Prodrug of Colchicine‐Site Binders for Selective Cancer Therapy

ChemMedChem, EarlyView.
This study presents a β‐glucuronidase‐responsive albumin‐binding prodrug enabling the selective release within the tumor microenvironment of an Isocombretastatin A‐4 analog. In triple‐negative breast cancer (TNBC) mouse models, this prodrug demonstrated significant tumor growth inhibition, highlighting potential for enhanced therapeutic selectivity and
Alexandra Bordes, Isabelle Opalinski, Fabien Thoreau, Olivier Provot, Abdallah Hamze, Mouad Alami, Sébastien Papot   +6 more
wiley   +1 more source