Results 31 to 40 of about 331,243 (309)

Mechanisms of Aerobic Exercise Impairment in Diabetes: A Narrative Review

Frontiers in Endocrinology, 2018
The prevalence of diabetes in the United States and globally has been rapidly increasing over the last several decades. There are now estimated to be 30.3 million people in the United States and 422 million people worldwide with diabetes.
Matthew P. Wahl, Matthew P. Wahl, Rebecca L. Scalzo, Rebecca L. Scalzo, Judith G. Regensteiner, Judith G. Regensteiner, Jane E. B. Reusch, Jane E. B. Reusch, Jane E. B. Reusch   +8 more
doaj   +1 more source

Prenatal exposure to a low dose of BPS causes sex-dependent alterations to vascular endothelial function in adult offspring

Frontiers in Toxicology, 2022
Background: Bisphenol S (BPS) is among the most commonly used substitutes for Bisphenol A (BPA), an endocrine disrupting chemical used as a plasticizer in the manufacture of polycarbonate plastics and epoxy resins.
Liam T. Connors, Liam T. Connors, Liam T. Connors, Hai-Lei Zhu, Hai-Lei Zhu, Manvir Gill, Emma Walsh, Emma Walsh, Radha D. Singh, Radha D. Singh, Radha D. Singh, Radha D. Singh, Sarah Easson, Sarah Easson, Sarah Easson, Sofia B. Ahmed, Sofia B. Ahmed, Hamid R. Habibi, William C. Cole, William C. Cole, William C. Cole, Jennifer A. Thompson, Jennifer A. Thompson, Jennifer A. Thompson, Jennifer A. Thompson   +24 more
doaj   +1 more source

Transdermal iontophoresis as an in-vivo technique for studying microvascular physiology [PDF]

, 2011
Assessment of microvascular function is of major importance in understanding the physiology of the vasculature and in investigating the vascular effects of pathological conditions.
Sjöberg, Folke, Erik Tesselaar, Tesselaar, Erik, Folke Sjöberg, Tesselaar, Erik,, Sjöberg, Folke,   +5 more
core   +1 more source

Invasive coronary physiology in patients with angina and non-obstructive coronary artery disease: a consensus document from the coronary microvascular dysfunction workstream of the British Heart Foundation/National Institute for Health Research Partnership [PDF]

, 2022
Nearly half of all patients with angina have non-obstructive coronary artery disease (ANOCA); this is an umbrella term comprising heterogeneous vascular disorders, each with disparate pathophysiology and prognosis.
Rahman, H., Hoole, S.P., Channon, K., UK Coronary Microvascular Dysfunction Working Group, Morris, Paul D, Kharbanda, Rajesh K, Divaka Perera, Channon, K, Petraco, Ricardo, Haseeb Rahman, Hoole, SP, Perera, D., Sinha, Aish, Ricardo Petraco, Keith Channon, Colin Berry, Paul D Morris, Channon, Keith, Stephen P Hoole, Morris, P.D., Hoole, Stephen P, Rajesh K Kharbanda, Rahman, Haseeb, Kharbanda, RK, Hoole, Stephen P., Kharbanda, R.K., Aish Sinha, Petraco, R, Kharbanda, Rajesh K., Perera, Divaka, Sinha, A., Morris, Paul D., Berry, Colin, Berry, C, Morris, PD, Berry, C., Perera, D, Sinha, A, Petraco, R., Rahman, H   +39 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Symposium 13: Impact of prediabetes on microvascular disease

Revista de la Sociedad Argentina de Diabetes, 2022
Many studies have reported that more than a third of adults newly diagnosed with type 2 diabetes have some degree of renal, retinal, or neuropathic damage from the onset of the disease, suggesting that the alterations that lead to microvascular disease ...
María Florencia Aranguren
doaj   +1 more source

Coronary Microvascular Dysfunction and Microvascular Angina

International Journal of Cardiovascular Practice, 2019
Many patients present with myocardial ischemic symptoms, but fail to be diagnosed of obstructed coronary artery disease, since the normal coronary arteries or no any atherosclerosis stenosis ≥ 50% at coronary angiography. Myocardial ischemia can be caused by either abnormalities of epicardial coronary arteries or coronary microvascular dysfunction (CMD)
Sun Yuhua, Wang Baoping
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Study the association of chronic obstructive pulmonary disease with early endothelial dysfunction and its impact on cardiovascular system by estimating urinary albumin creatinine ratio

Lung India, 2017
Background: Chronic obstructive pulmonary disease (COPD) attribute to systemic inflammation which is responsible for microalbuminuria reflecting endothelial dysfunction, could be a significant surrogate marker of potential cardiovascular morbidity ...
Anand Agrawal, Renu Garg, Dibakar Sahu, Mukesh Kumar   +3 more
doaj   +1 more source