Results 51 to 60 of about 303,956 (318)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Transdermal iontophoresis as an in-vivo technique for studying microvascular physiology

, 2011
Assessment of microvascular function is of major importance in understanding the physiology of the vasculature and in investigating the vascular effects of pathological conditions.
Sjöberg, Folke, Erik Tesselaar, Tesselaar, Erik, Folke Sjöberg, Tesselaar, Erik,, Sjöberg, Folke,   +5 more
core   +1 more source

Genetics of Diabetic Microvascular Disease [PDF]

, 2020
Diabetic microvascular complications, affecting the kidneys, retina, and the nervous system, are a heavy burden for both the diabetic individual and society.
Carol Forsblom, Niina Sandholm, Forsblom, Carol, Sandholm, Niina   +3 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

The role of probiotics on microvascular complications of type-2 diabetes: Nephropathy and retinopathy [PDF]

Journal of Cardiovascular and Thoracic Research
Diabetes is a multifactorial disorder that involves several molecular mechanisms and is still one of the key global health challenges with increasing prevalence and incidence.
Robab Sarmadi, Hajie Lotfi, Mohammad Amin Hejazi, Fariba Ghiasi, Rana Keyhanmanesh   +4 more
doaj   +1 more source

Microvascular abnormalities in dry eye patients

, 2018
This study was conducted to evaluate conjunctival blood flow velocities and microvascular network density in patients with dry eye disease (DED). Twenty-five patients with DED and 25 healthy controls were recruited.
Chen, Wan, Wang, Bowen, Li, Saiqun, Deng, Yuqing, Saiqun Li, Yuan, Jin, Peng, Lulu, Hong Jiang, Bowen Wang, Yang, Ruhui, Zhang, Henan, Wan Chen, Ruhui Yang, Li, Meng, Jianhua Wang, Zhong, Jing, Lulu Peng, Henan Zhang, Yuqing Deng, Meng Li, Wang, Jianhua, Jing Zhong, Jin Yuan, Jiang, Hong   +23 more
core   +1 more source

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park, Emily J. Koubek, Richard Beare, Lynn Ang, Brian C. Callaghan, Rodica Pop‐Busui, Eva L. Feldman, Evan L. Reynolds   +7 more
wiley   +1 more source

Nerve Autografts Versus Allografts for Mixed Motor/Sensory Nerve Reconstruction

Journal of Hand Surgery Global Online
Reconstruction of peripheral mixed motor/sensory nerves using autografts has remained the gold standard. Inconsistent and nonphysiologic results across nerve allograft studies, including successful and failed motor reinnervation, have limited the current
Sara Saffari, MD, MSc, Alexander Y. Shin, MD, Nicholas Pulos, MD   +2 more
doaj   +1 more source

Acidosis in muscle tissue distal to vascular contusion despite unchanged global blood flow in rats : An uncoupling of microvascular blood flow and metabolism?

, 2005
Studies using a contusion trauma model have shown that the femoral artery of the rat remains patent in 85% despite a severe vessel injury. A significant increase in tissue oxygenation (PtO2) has been found despite only a minor effect on blood flow (
Karlander, Lars-Erik,, Henriksson, J,, Sjöberg, F, Henriksson, J, Karlander, LE, Sjöberg, Folke,   +5 more
core   +1 more source