Results 181 to 190 of about 132,725 (259)

Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score

ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.
Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher, Kensuke Matsushita, Shinnosuke Kikuchi, Taraneh Tatarcheh, Benjamin Marchandot, Amandine Granier, Said Amissi, Antonin Trimaille, Laurence Jesel, Patrick Ohlmann, Kiyoshi Hibi, Valérie Schini‐Kerth, Olivier Morel   +12 more
wiley   +1 more source

Microvascular Dysfunction in MINOCA: Still a Moving Target. [PDF]

J Am Heart Assoc
Cenko E, Manfrini O, Bugiardini R.
europepmc   +1 more source

Inhibition of adenosine kinase alleviates hypertrophic cardiomyopathy by ameliorating coronary microvascular dysfunction. [PDF]

ESC Heart Fail
Wan F, Ma B, Han Z, Zheng Y, Lu M, Chen J, Wang J, Song L.   +7 more
europepmc   +1 more source

Microvascular Abnormalities in Adolescents With Anorexia Nervosa: Nailfold Video Capillaroscopic Evidence at Acute and Remission States

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Chronic malnutrition, hypothermia, and hormonal imbalance in anorexia nervosa (AN) may impair capillary structure and perfusion. This study aimed to describe the nailfold videocapillaroscopy (NVC) findings in adolescents with AN and atypical AN (AAN), to assess their association with Raynaud's phenomenon (RP), and evaluate ...
Muserref Kasap‐Cuceoglu, Melis Pehlivanturk‐Kizilkan, Erdal Sag, Seher Sener, Zeynep Balik, Sinem Akgul, Orhan Derman, Yelda Bilginer, Nuray Kanbur, Seza Özen   +9 more
wiley   +1 more source

Insulin resistance and coronary microvascular dysfunction: a complex interplay. [PDF]

Cardiovasc Diabetol
Magistri M, Portolan L, Trevisanello A, Tosi F, Locatelli A, Piana S, Rubinelli M, Molinaroli E, Mantovani A, Ribichini F, Kunadian V, Bonadonna R, Scarsini R.   +12 more
europepmc   +1 more source

Targeting eEF1A1 With Baicalein to Block eEF1A1/Prdx4 Interaction for Treating Sepsis‐Mediated Lung Injury

Exploration, EarlyView.
Targeting eEF1A1 with baicalein disrupts the eEF1A1‐Prdx4 interaction to prevent RNF14‐mediated ubiquitination and degradation of Prdx4. This stabilizes Prdx4 to suppress NF‐κB, thereby alleviating sepsis‐induced acute lung injury. ABSTRACT Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection ...
Jing Chang, Hui‐Lin Zhang, Qi‐Meng Zhu, Si‐Wen Hui, Xin‐Rong Xu, Mahmood Brobbey Oppong, Yan‐Li Feng, Juan Zhang, Cheng‐Peng Sun, Feng Qiu   +9 more
wiley   +1 more source

Coronary Microvascular Dysfunction and Lipid Molecules: Pathophysiological Mechanisms, Clinical Assessment, and Therapeutic Implications. [PDF]

J Pers Med
Hafez A, Farina JM, Awad K, Pietri MP, Scalia IG, Sheashaa H, Abdelfattah FE, Razaghi M, Ahmed S, Ibrahim R, Simper D, Lester SJ, Tamarappoo B, Ayoub C, Arsanjani R.   +14 more
europepmc   +1 more source

Probiotic Spore Inspired Oral Drug Delivery System With Multiple‐Barriers‐Crossing Ability Modulates Gut‐Brain Axis for Parkinson's Disease Therapy

Exploration, EarlyView.
Inspired by the germination of probiotic spores, we utilize the excellent characteristics of spores to break through multiple barriers of oral brain‐targeted delivery. Besides the probiotics mediated gut‐brain communication, the spore coat proteins derived nanosystems with multiple‐barriers‐crossing ability alleviate neurodegeneration.
Qianhua Feng, Yuying Mei, Jia Zhang, Liying Sun, Bingqian Si, Huimin Zhou, Huifang Xiao, Runhan Liu, Jieyun Zhang, Lei Wang   +9 more
wiley   +1 more source

Retinal Microvascular Dysfunction Reflects Vascular and Alzheimer's-Related Pathology in Dementia With Lewy Bodies. [PDF]

CNS Neurosci Ther
Tong Q, Kwapong WR, Luan X, Hu S, Hu Y, Guo Y, Ji C, Yang M, Wang Z.   +8 more
europepmc   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source