Results 251 to 260 of about 193,314 (299)

The Mechanisms Associated with Inflammation and Coronary Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction. [PDF]

Med Princ Pract
Yan X, Wang R, Xu H, Tao Z, Ling J.
europepmc   +1 more source

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu, Wen‐Juan Wang, Ting‐Ting Zhang, Qi‐Chong Yang, Haliminai Dilimulati, Song‐Tao An   +5 more
wiley   +1 more source

Impact of Procedural Differences on Bolus Thermodilution Method for Assessment of Coronary Microvascular Dysfunction. [PDF]

Catheter Cardiovasc Interv
Hirano S, Yabe T, Okubo R, Amano H, Ikeda T.   +4 more
europepmc   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

Coronary Microvascular Dysfunction Alters the Pulsatile Behavior of the Resting Coronary Blood Flow. [PDF]

Microcirculation
Tas A, Alan Y, Tas IK, Aydin OE, Atay Z, Yilmaz S, Ozcan A, van de Hoef TP, Umman S, Piek Md JJ, Sezer M.   +10 more
europepmc   +1 more source

Molecular Mechanism of the IRF1/NFE2L1‐DT/ALKBH5/Cx43 Axis in Radiation‐Induced Injury in Vascular Endothelial Cells Through Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li, Jia‐Wen Yang, Yong‐Rui Jia, Jie Zhang, Qiao Gou   +4 more
wiley   +1 more source

Persistent Impairment of Coronary Microvascular Dysfunction After Percutaneous Coronary Intervention in an Ice Swimming Champion. [PDF]

J Med Cases
Kone G, Godin M, Fuzeau A, Verdonck A, Raoux F, Dacher JN, Neuvillers L, Le Moal J, Landolff Q.   +8 more
europepmc   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

Coronary Microvascular Dysfunction in Ischaemic Heart Disease: Lessons From Large Animal Models. [PDF]

Basic Clin Pharmacol Toxicol
Sorop O, van de Wouw J, Merkus D, Duncker DJ.   +3 more
europepmc   +1 more source

Persistent Angina With Nonobstructive Coronary Artery Disease: Unmasking Coronary Microvascular Dysfunction Post-Oncotherapy. [PDF]

JACC Case Rep
Macanovic P, Cheng K, Ramasamy A, Baksi J, de Silva R.   +4 more
europepmc   +1 more source