Results 91 to 100 of about 70,906 (304)

Modeling smooth muscle cell–endothelial cell crosstalk in abdominal aortic aneurysms using 3D microvessels on-chip

Vascular Biology
Abdominal aortic aneurysms (AAAs) are pathological dilations of the abdominal aorta. To date, surgical intervention has been the only option for managing large AAAs, with no pharmacological therapies to prevent growth of small aneurysms.
Philipp C Hauger, Karlijn B Rombouts, Marc Vila Cuenca, Albert van Wijk, Max C Overboom, Jan Willem Buikema, Kak Khee Yeung, Valeria V Orlova, Peter L Hordijk   +8 more
doaj   +1 more source

Differences in Microvasculature between Ethylnitrosourea-induced Brain Tumor and Transplanted 9L Cell Brain Tumor in the Rat

, 1989
The microvasculature of ethylnitrosourea (ENU)-induced brain tumors and transplanted 9L cell brain tumors were studied in ultrathin sections and by the freeze fracture replica method. The vessels in ENU-induced tumors were similar to human glioma vessels
陣内, 敬文, 柴田, 尚武, 森, 和夫, 福嶋, 政昭   +3 more
core  

Hemoglobin's α‐Helix‐to‐β‐Sheet Transition Enables Targeted mRNA Delivery to the Lung

Advanced Science, EarlyView.
Acidic heating converts hemoglobin into β‐sheet‐rich fibrils with positively charged surfaces. These hemoglobin fibrils electrostatically complex IL‐11 scFv mRNA, selectively bind circulating platelets, and hitchhike to the lung, where they are enriched in fibroblasts.
Xihua Liu, Saiya Li, Guodong Wu, Shuangjian Li, Long Shuang Huang, Xiaoyang Li, Yiguo Zhao, Wei Lu, Cuixia Sun, Qin Cao, Yapeng Fang, Yiping Cao   +11 more
wiley   +1 more source

Lipoprotein (a) in the Development and Progression of Diabetic Retinopathy: A Systematic Review and Meta-Analysis

Medicina
Background and Objectives: Diabetic retinopathy (DR) is a significant complication of Diabetes Mellitus. Several studies have indicated Lipoprotein (a) [Lp(a)] plays a role in atherosclerotic alterations.
Stamatios Lampsas, Vaia Lambadiari, Chrysa Agapitou, Aikaterini Lampsa, Evangelos Oikonomou, Gerasimos Siasos, Irini Chatziralli   +6 more
doaj   +1 more source

Effects of a facial nerve lesion on responses in forehead microvessels to conjunctival irritation and paced breathing

, 2012
To investigate parasympathetic influences on the forehead microvasculature, blood flow was monitored bilaterally in seven participants with a unilateral facial nerve lesion during conjunctival irritation with Schirmer's strips and while breathing at 0.15.
Drummond, P.D.
core  

Spectral analysis of the microvasculature of primary cutaneous melanoma.

, 2010
peer reviewedCutaneous malignant melanoma represents one of the most dramatic skin cancers because its incidence is steadily growing in White populations.
PIERARD, Gérald, Quatresooz, Pascale, Humbert, Philippe, Pierard, Sébastien, Piérard-Franchimont, Claudine, Piérard, Gerald, E., FRANCHIMONT, Claudine   +6 more
core   +1 more source

Retinal Vessel Segmentation: A Comprehensive Review From Classical Methods to Deep Learning Advances (1982–2025)

Advanced Intelligent Systems, EarlyView.
Four decades of retinal vessel segmentation research (1982–2025) are synthesized, spanning classical image processing, machine learning, and deep learning paradigms. A meta‐analysis of 428 studies establishes a unified taxonomy and highlights performance trends, generalization capabilities, and clinical relevance.
Avinash Bansal, Jan Kubíček, Jana Bahrová, Alice Varyšová, Martin Augustýnek, Marek Penhaker, Juraj Timkovič   +6 more
wiley   +1 more source

Euglycemic Hyperinsulinemia Lowers Blood Pressure and Impedes Microvascular Perfusion More Effectively in Persons with Cardio-Metabolic Disease

Endocrines
In healthy humans, insulin at physiological concentrations exerts acute vasodilatory actions on both resistance and terminal arterioles, leading, respectively, to increased total blood flow and the microvascular network volume being perfused. The process
Zhenqi Liu, Linda A. Jahn, Eugene J. Barrett   +2 more
doaj   +1 more source

Invasive Assessment of the Coronary Microvasculature

, 2017
Traditionally, invasive coronary physiological assessment has focused on the epicardial coronary artery. More recently, appreciation of the importance of the coronary microvasculature in determining patient outcomes has grown. Several invasive modalities
Yuhei Kobayashi, William F. Fearon
core   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source