Results 21 to 30 of about 30,901 (212)

Tethered Signaling in Inhibitory Immune Receptors

open access: yesFrontiers in Physics, 2019
Leukocytes play critical roles in preventing pathogenic infection and controlling transformed cells, but must remain quiescent in response to healthy tissue.
Pablo Pérez-Ferreros   +5 more
doaj   +1 more source

Dual Role of CD4 in Peripheral T Lymphocytes

open access: yesFrontiers in Immunology, 2019
The interaction of T-cell receptors (TCRs) with self- and non-self-peptides in the major histocompatibility complex (MHC) stimulates crucial signaling events, which in turn can activate T lymphocytes.
Daniela Glatzová   +2 more
doaj   +1 more source

Intercellular communication in the cumulus–oocyte complex during folliculogenesis: A review

open access: yesFrontiers in Cell and Developmental Biology, 2023
During folliculogenesis, the oocyte and surrounding cumulus cells form an ensemble called the cumulus-oocyte complex (COC). Due to their interdependence, research on the COC has been a hot issue in the past few decades.
Jun Xie, Xiao Xu, Suying Liu
doaj   +1 more source

Move your microvilli [PDF]

open access: yesJournal of Cell Biology, 2014
Polarized epithelial cells create tightly packed arrays of microvilli in their apical membrane, but the fate of these microvilli is relatively unknown when epithelial cell polarity is lost during wound healing. In this issue, Klingner et al. (2014. J. Cell Biol.
openaire   +2 more sources

T Cell Membrane Heterogeneity Aids Antigen Recognition and T Cell Activation

open access: yesFrontiers in Cell and Developmental Biology, 2020
T cells are critical for co-ordinating the immune response. T cells are activated when their surface T cell receptors (TCRs) engage cognate antigens in the form of peptide-major histocompatibility complexes (pMHC) presented on the surface of antigen ...
Megan V. Farrell   +7 more
doaj   +1 more source

T Cell Microvilli: Sensors or Senders?

open access: yesFrontiers in Immunology, 2019
Communication between cells is essential for multicellular life. During cognate immune interactions, T cells communicate with antigen-presenting cells (APC) via direct cell–cell contact or the release of molecules and vesicles containing T cell messages.
Hye-Ran Kim   +3 more
doaj   +1 more source

Oxidative Stress Boosts the Uptake of Cerium Oxide Nanoparticles by Changing Brain Endothelium Microvilli Pattern

open access: yesAntioxidants, 2021
Vascular oxidative stress is considered a worsening factor in the progression of Alzheimer’s disease (AD). Increased reactive oxygen species (ROS) levels promote the accumulation of amyloid-β peptide (Aβ), one of the main hallmarks of AD.
Roberta Dal Magro   +12 more
doaj   +1 more source

ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation

open access: yesCell Reports, 2020
Summary: T cell surfaces are covered with microvilli, actin-rich and flexible protrusions. We use super-resolution microscopy to show that ≥90% of T cell receptor (TCR) complex molecules TCRαβ and TCRζ, as well as the co-receptor CD4 (cluster of ...
Shirsendu Ghosh   +9 more
doaj   +1 more source

Mechanosurveillance: Tiptoeing T Cells

open access: yesFrontiers in Immunology, 2022
Efficient scanning of tissue that T cells encounter during their migratory life is pivotal to protective adaptive immunity. In fact, T cells can detect even a single antigenic peptide/MHC complex (pMHC) among thousands of structurally similar yet non ...
Janett Göhring   +4 more
doaj   +1 more source

Effects of honey saccharide supplementation on growth performance, amylase enzyme activity, gut microvilli, and microbiome in Cyprinus carpio [PDF]

open access: yesVeterinary World
Background and Aim: Prebiotics, such as saccharides in honey, play a crucial role in improving gut microbiota, digestion, and immune function. This study evaluates the effects of Kapok flower honey saccharides on growth performance, digestive enzyme ...
Yani Aryati   +9 more
doaj   +1 more source

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