Results 31 to 40 of about 57,043 (220)

T Cell Microvilli: Sensors or Senders?

Frontiers in Immunology, 2019
Communication between cells is essential for multicellular life. During cognate immune interactions, T cells communicate with antigen-presenting cells (APC) via direct cell–cell contact or the release of molecules and vesicles containing T cell messages.
Hye-Ran Kim, Hye-Ran Kim, Chang-Duk Jun, Chang-Duk Jun   +3 more
doaj   +1 more source

T Cell Membrane Heterogeneity Aids Antigen Recognition and T Cell Activation

Frontiers in Cell and Developmental Biology, 2020
T cells are critical for co-ordinating the immune response. T cells are activated when their surface T cell receptors (TCRs) engage cognate antigens in the form of peptide-major histocompatibility complexes (pMHC) presented on the surface of antigen ...
Megan V. Farrell, Megan V. Farrell, Samantha Webster, Samantha Webster, Katharina Gaus, Katharina Gaus, Jesse Goyette, Jesse Goyette   +7 more
doaj   +1 more source

Oxidative Stress Boosts the Uptake of Cerium Oxide Nanoparticles by Changing Brain Endothelium Microvilli Pattern

Antioxidants, 2021
Vascular oxidative stress is considered a worsening factor in the progression of Alzheimer’s disease (AD). Increased reactive oxygen species (ROS) levels promote the accumulation of amyloid-β peptide (Aβ), one of the main hallmarks of AD.
Roberta Dal Magro, Agostina Vitali, Stefano Fagioli, Alberto Casu, Andrea Falqui, Beatrice Formicola, Lorenzo Taiarol, Valeria Cassina, Claudia Adriana Marrano, Francesco Mantegazza, Umberto Anselmi-Tamburini, Patrizia Sommi, Francesca Re   +12 more
doaj   +1 more source

ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation

Cell Reports, 2020
Summary: T cell surfaces are covered with microvilli, actin-rich and flexible protrusions. We use super-resolution microscopy to show that ≥90% of T cell receptor (TCR) complex molecules TCRαβ and TCRζ, as well as the co-receptor CD4 (cluster of ...
Shirsendu Ghosh, Vincenzo Di Bartolo, Liron Tubul, Eyal Shimoni, Elena Kartvelishvily, Tali Dadosh, Sara W. Feigelson, Ronen Alon, Andres Alcover, Gilad Haran   +9 more
doaj   +1 more source

Small and large intestine express a truncated Dab1 isoform that assembles in cell-cell junctions and co-localizes with proteins involved in endocytosis [PDF]

, 2018
Disabled-1 (Dab1) is an essential intracellular adaptor protein in the reelin pathway. Our previous studies in mice intestine showed that Dab1 transmits the reelin signal to cytosolic signalling pathways.
Balda, María S., García Miranda, Pablo, Ilundáin Larrañeta, María Anunciación Ana, Matter, Karl, Peral Rubio, María José, Vázquez Carretero, María Dolores   +5 more
core   +1 more source

Models of dynamic extraction of lipid tethers from cell membranes [PDF]

, 2010
When a ligand that is bound to an integral membrane receptor is pulled, the membrane and the underlying cytoskeleton can deform before either the membrane delaminates from the cytoskeleton or the ligand detaches from the receptor.
Cuvelier D, Lodish H, Morris C E, Sarah A Nowak, Tom Chou   +4 more
core   +1 more source

Mechanosurveillance: Tiptoeing T Cells

Frontiers in Immunology, 2022
Efficient scanning of tissue that T cells encounter during their migratory life is pivotal to protective adaptive immunity. In fact, T cells can detect even a single antigenic peptide/MHC complex (pMHC) among thousands of structurally similar yet non ...
Janett Göhring, Janett Göhring, Lukas Schrangl, Gerhard J. Schütz, Johannes B. Huppa   +4 more
doaj   +1 more source

Inner-ear abnormalities and their functional consequences in Belgian Waterslager canaries (Serinus canarius) [PDF]

, 1994
Recent reports of elevated auditory thresholds in canaries of the Belgian Waterslager strain have shown that this strain has an inherited auditory deficit in which absolute auditory thresholds at high frequencies (i.e. above 2.0 kHz) are as much as 40 dB
Brown, Cleveland, Corwin, Cotanche, Cotanche, Cotanche, Cousillas, Dooling, Dooling, Fischer, Geoffrey A. Manley, Girod, Girod, Gleich, Gleich, Gleich, Gleich, Gleich, Gummer, Guttinger, Hashino, Hashino, Köppl, Manley, Manley, Manley, Marler, Nottebohm, Okanoya, Okanoya, Okanoya, Okanoya, Okanoya, Otto Gleich, Patuzzi, Pickles, Robert J. Dooling, Saunders, Steel, Steel, Stresemann, Tilney, Waser   +42 more
core   +1 more source

Histological Investigations on an Intestinal Level in Common Carp, One Summer Old, Fed with Organic Selenium (Selplex) Supplemented Fodder

Scientific Papers Animal Science and Biotechnologies, 2023
The goal of this research was to analyze the effect of organic Selenium (SelPlex) on the intestinal mucosa and the impact on the growth and consumption performances in one summer old common carp (Cyprinus carpio), Lausitz and Galitian varieties.
Aurel Șara, Alina Rodica Ani (Toma), Florin Molnar, Erol Gabor   +3 more
doaj  

Effects of honey saccharide supplementation on growth performance, amylase enzyme activity, gut microvilli, and microbiome in Cyprinus carpio [PDF]

Veterinary World
Background and Aim: Prebiotics, such as saccharides in honey, play a crucial role in improving gut microbiota, digestion, and immune function. This study evaluates the effects of Kapok flower honey saccharides on growth performance, digestive enzyme ...
Yani Aryati, Ekorini Farastuti, Lili Sholichah, Isti Koesharyani, Lila Gardenia, Early Septiningsih, Muhamad Yamin, Parwa Oryzanti, Dewi Puspaningsih, Desy Sugiani   +9 more
doaj   +1 more source