Results 171 to 180 of about 151,098 (403)

Pharmacokinetics of midazolam in CYP3A4- and CYP3A5-genotyped subjects [PDF]

, 2018
Objective: We investigated whether differences in pharmacokinetics of midazolam, a CYP3A probe, could be demonstrated between subjects with different CYP3A4 and CYP3A5 genotypes.
Aubert, Anne-Catherine, Baumann, Pierre, Bleiber, Gabriela, Buclin, Thierry, Eap, Chin, Golay, Kerry, Hustert, Elisabeth, Kerb, Reinhold, Telenti, Amalio   +8 more
core  

Evaluation of the Pharmacokinetics, Disposition, and Metabolism of Miricorilant, a Novel Glucocorticoid Receptor Modulator for the Treatment of Metabolic Dysfunction‐Associated Steatohepatitis in Nonclinical and Clinical Studies

The Journal of Clinical Pharmacology, EarlyView.
Abstract Miricorilant is a novel selective glucocorticoid receptor (GR) modulator with mixed agonist/antagonist effects at the GR and modest antagonism at the mineralocorticoid receptor that is being developed for the treatment of metabolic dysfunction‐associated steatohepatitis.
Hazel J. Hunt, Kirsteen M. Donaldson, Jeevan R. Kunta, Joseph M. Custodio   +3 more
wiley   +1 more source

PHARMACOKINETICS OF MIDAZOLAM IN TOTAL I. V. ANAESTHESIA

, 1987
Peter M. Persson, Anders Nilsson, Per Hartvig, A. Tamsen   +3 more
openalex   +1 more source

The Art of Reception: Field Visits as Microcosms for Development Interventions of Non‐Governmental Organisations in Uganda

Journal of International Development, EarlyView.
ABSTRACT Field visits are common phenomena with non‐governmental organisations in Uganda. During these visits, Ugandan national staff guide visitors on series of meetings and interactions in the field. Following an actor‐oriented approach and drawing on ethnographic data on 14 field visits, this paper understands the field visit as a microcosm for the ...
Caspar Edward Swinkels
wiley   +1 more source

Comparison of propofol‐based sedation and midazolam sedation in pediatric bidirectional endoscopy conducted by pediatric gastroenterologists

DEN Open
Objectives The effectiveness and safety of propofol‐based sedation and midazolam sedation in pediatric bidirectional endoscopy were compared. Methods We retrospectively analyzed the cases of pediatric patients (≤15 years old) who had undergone ...
Takahiro Kudo, Satomi Nishimoto, Ichitaro Horiuchi, Shingo Kurasawa, Satoshi Ukai, Akira Horiuchi   +5 more
doaj   +1 more source

DOUBLE-BLIND STUDY OF THE REVERSAL OF MIDAZOLAM-SUPPLEMENTED GENERAL ANAESTHESIA WITH RO 15–1788 †

, 1987
Eli Alon, L.C. BAITELLA, G Hossli
openalex   +1 more source

Safety of MRI Examinations Under Sedation: A Nationwide Survey in Japan

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI is performed under sedation for patients requiring immobility or for those already sedated for clinical management. Although specialist guidelines advocate for anesthesiologist‐led care, non‐anesthesiologist‐led adult sedation is a common practice worldwide. Furthermore, the increase in risk attributable to sedation has not been
Shiori Amemiya, Masako Kataoka, Tsukasa Doi, Toshinori Hirai, Takayuki Obata, Kagayaki Kuroda   +5 more
wiley   +1 more source

MIDAZOLAM SEDATION FOLLOWING OPEN HEART SURGERY

, 1987
Hannah Morris Mathews, Ian Carson, Paul S. Collier, JOHN W. DUNDEE, Kayleigh Fitzpatrick, P.J. HOWARD, Seán Lyons, I.A. Orr   +7 more
openalex   +1 more source

Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander, Tudor M. Ionescu, Mitul A. Mehta, Ottavia Dipasquale, Anouk Schrantee   +4 more
wiley   +1 more source

SEDATION FOR ENDOSCOPY: MIDAZOLAM OR DIAZEPAM AND PETHIDINE?

, 1988
D.A.R. Boldy, L.R. Lever, P.R. UNWIN, Paulette Spencer, A M Hoare   +4 more
openalex   +1 more source