Results 301 to 310 of about 145,146 (385)

Microbiota diversity and differences in the respiratory tract of children with pneumonia

Pediatric Investigation, EarlyView.
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge, Lingyun Hou, Jintao Guo, Xuejing Lv, Yungang Yang   +4 more
wiley   +1 more source

Ketamine administration for rigid bronchoscopy in adult: literary review and the operator perception. [PDF]

J Thorac Dis
Tacchi G, Frasca L, Longo F, Sarubbi A, Marziali V, Suriano I, Costa F, Crucitti P.   +7 more
europepmc   +1 more source

EFFECT OF FLUMAZENIL ON MIDAZOLAM-INDUCED AMNESIA

, 1990
A.C. MCKAY, M. S. McKinney, R.S.J. CLARKE   +2 more
openalex   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Impact of Video Distraction on Anxiety During Anesthesia Induction in Pediatric Patients Premedicated With Midazolam: A Randomized Controlled Trial. [PDF]

Paediatr Anaesth
Sablewski A, Jacobi T, Walter S, Muhle H, Kandzia C, Fazel A, Meinzer A, Melchior DA, Caliebe A, Kalab M, Becher T, Lautenschläger I.   +11 more
europepmc   +1 more source

Slow Injection Does Not Prevent Midazolam-Induced Ventilatory Depression

, 1992
Christian M. Alexander, Lynne E. Teller, Jeffrey B. Gross   +2 more
openalex   +1 more source

Development and Verification of a Physiologically Based Pharmacokinetic Model of Furmonertinib and Its Main Metabolite for Drug–Drug Interaction Predictions

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Furmonertinib demonstrated potent efficacy as a newly developed tyrosine kinase inhibitor for the treatment of patients with epidermal growth factor receptor (EGFR) mutation‐positive non‐small cell lung cancer. In vitro research showed that furmonertinib is metabolized to its active metabolite AST5902 via the cytochrome P450 (CYP) enzyme ...
Yali Wu, Helena Leonie Hanae Loer, Yifan Zhang, Dafang Zhong, Yong Jiang, Jie Hu, Uwe Fuhr, Thorsten Lehr, Xingxing Diao   +8 more
wiley   +1 more source

Opioid-Induced Myoclonus During Premedication in Two Dogs With Hydrocephalus Proactively Managed With Antiepileptic Medications. [PDF]

Vet Med Sci
Nam C, Lee I, Son WG.
europepmc   +1 more source

Enhancing Elementary Students Conceptual Understandings of Scientific Phenomena: The Impact of STEAM‐First and STEM‐First Approaches

Science Education, EarlyView.
ABSTRACT This study delves into the realm of student conceptual change, examining shifting understandings as important steppingstones on the path to sensemaking and canonical understanding in science education. It explores the potential of a STEAM (Science, Technology, Engineering, Arts, and Math) curriculum, aiming to provide equitable learning ...
Michael W. Corrigan, Joseph T. Wong, Doug Grove, Sage Andersen, Bradley S. Hughes   +4 more
wiley   +1 more source