Results 341 to 350 of about 145,146 (385)
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Anesthesiology, 1985
Midazolam is an imidazobenzodiazepine with unique properties when compared with other benzodiazepines. It is water soluble in its acid formulation but is highly lipid soluble in vivo. Midazolam also has a relatively rapid onset of action and high metabolic clearance when compared with other benzodiazepines. The drug produces reliable hypnosis, amnesia,
H. Ronald Vinik +3 more
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Midazolam is an imidazobenzodiazepine with unique properties when compared with other benzodiazepines. It is water soluble in its acid formulation but is highly lipid soluble in vivo. Midazolam also has a relatively rapid onset of action and high metabolic clearance when compared with other benzodiazepines. The drug produces reliable hypnosis, amnesia,
H. Ronald Vinik +3 more
openaire +3 more sources
Anaesthesia, 1983
SummaryMidazolam, administered intramuscularly was compared with papaveretum and hyoscine for premedication in patients undergoing gynaecological surgery. Midazolam proved to be a satisfactory agent for premedication compared with papaveretum and hyoscine, producing a similar degree of sedation and anxiolysis, but causing significantly more anterograde
J. Dixon, E. J. McATEER, J. G. Whitwam
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SummaryMidazolam, administered intramuscularly was compared with papaveretum and hyoscine for premedication in patients undergoing gynaecological surgery. Midazolam proved to be a satisfactory agent for premedication compared with papaveretum and hyoscine, producing a similar degree of sedation and anxiolysis, but causing significantly more anterograde
J. Dixon, E. J. McATEER, J. G. Whitwam
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American Journal of Veterinary Research, 2018
OBJECTIVE To compare sedation in cockatiels (Nymphicus hollandicus) after intranasal administration of midazolam and midazolam-butorphanol. ANIMALS 9 healthy adult cockatiels.
G. Doss, D. Fink, C. Mans
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OBJECTIVE To compare sedation in cockatiels (Nymphicus hollandicus) after intranasal administration of midazolam and midazolam-butorphanol. ANIMALS 9 healthy adult cockatiels.
G. Doss, D. Fink, C. Mans
semanticscholar +1 more source
Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children.
American Journal of Respiratory and Critical Care Medicine, 2016RATIONALE Various in vitro, animal, and limited human adult studies suggest a profound inhibitory effect of inflammation and disease on cytochrome P-450 3A (CYP3A)-mediated drug metabolism. Studies showing this relationship in critically ill patients are
N. Vet +10 more
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Midazolam and flumazenil in ophthalmology
Acta Anaesthesiologica Scandinavica, 1990Midazolam's pharmacodynamic properties are used in ophthalmology in several indications: 1. to relieve anxiety and unwanted reactions during radial keratotomy in ambulatory patients; 2. to provide sedation and amnesia during cataract surgery using local anaesthesia, in combination with low doses of phenoperidine; 3.
D. Gobeaux, F. Sardnal
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Neurotoxicity of midazolam in the rabbit
Pain, 1999Safe and efficient use of spinal drugs requires neurotoxicologic animal studies before ethical application. We have evaluated the neurotoxicologic interruptions of intrathecal administration of midazolam in rabbits. Eighteen white New Zealand rabbits were randomly assigned into three groups consisting of six rabbits each. In conscious animals, 0.3 ml 0.
Nejat Savci +7 more
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Midazolam and flumazenil in gastroenterologys
Acta Anaesthesiologica Scandinavica, 1990Flumazenil, a specific benzodiazepine antagonist, has been used to reverse sedation in a double‐blind, controlled study of patients undergoing upper gastrointestinal (GI) endoscopy. Forty patients in each of two centres were given a standard dose of either flumazenil (n = 40) or placebo (n = 40) after gastroscopy under midazolam sedation.
K. D. Bardhan +3 more
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The Chronic Efficacy of Midazolam
International Clinical Psychopharmacology, 1990The chronic efficacy of midazolam 15.0 mg was studied in 2 male and 10 female subjects. Only subjects with a complaint of sleep latency insomnia which was verified by polysomnography were included in the study. Following a screening and adaptation period, subjects spent 3 consecutive nights in the laboratory during the weeks of the study.
James Lamphere +5 more
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Midazolam and flumazenil in neuroanaesthesia
Acta Anaesthesiologica Scandinavica, 1990Of the numerous benzodiazepines currently available, only a few are used in anaesthetic practice. Midazolam is utilised as a premedicant, sedative, and an induction agent and produces minimal depression of ventilation or of the cardiovascular system. The anticonvulsant activity is similar to that of diazepam.
Eberhard Kochs, J. Schulte am Esch
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Flumazenil and midazolam in anaesthesia
Acta Anaesthesiologica Scandinavica, 1995Flumazenil, the first benzodiazepine antagonist, is currently used widely as an emergency drug, and has also been utilized in planned procedures, to time arousal intra‐ or post‐operatively. It is known that flumazenil, used at the end of a procedure, causes instant recovery by reversing the residual effects of, for example, midazolam.
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