Results 211 to 220 of about 212,558 (382)

Differentiation of ciliated human midbrain-derived LUHMES neurons [PDF]

, 2020
Gilbert Lauter, Andrea Coschiera, Masahito Yoshihara, Debora Sugiaman‐Trapman, Sini Ezer, Shalini Sethurathinam, Shintaro Katayama, Juha Kere, Peter Swoboda   +8 more
openalex   +1 more source

Patient‐Derived Neurons Exhibit α‐Synuclein Pathology and Previously Unrecognized Major Histocompatibility Complex Class I Elevation in Mitochondrial Membrane Protein–Associated Neurodegeneration

Movement Disorders, EarlyView.
Abstract Background Mitochondrial membrane protein–associated neurodegeneration (MPAN) from the neurodegeneration with brain iron accumulation (NBIA) family is a rare neurodegenerative disease marked by α‐synuclein aggregation, brain iron accumulation, and midbrain dopaminergic neuron degeneration.
Leonie M. Heger, Leonie Kertess, Clara Kaufhold, Francesco Gubinelli, Aida Cardona‐Alberich, Gamze Özata, Stephan A. Müller, Sarah K. Tschirner, Oliver Stehling, Martina Schifferer, Camille Peron, Valeria Tiranti, Roland Lill, Arcangela Iuso, Luigi Zecca, Michael Strupp, Wolfgang Oertel, Stefan F. Lichtenthaler, Lena F. Burbulla   +18 more
wiley   +1 more source

Efficient Conversion of Astrocytes to Functional Midbrain Dopaminergic Neurons Using a Single Polycistronic Vector

, 2011
Russell C. Addis, Fu‐Chun Hsu, Rebecca Wright, Marc A. Dichter, Douglas A. Coulter, John D. Gearhart   +5 more
openalex   +2 more sources

Vagus Nerve Stimulation in Movement Disorders, from Principles to a Systematic Review of Evidence

Movement Disorders, EarlyView.
Abstract Background The vagus nerve (VN), the principal component of the parasympathetic branch of the autonomic nervous system (ANS), mediates bidirec communication between the central nervous system (CNS) and peripheral organs. Vagus nerve stimulation (VNS), delivered through invasive (iVNS) or non‐invasive (transcutaneous cervical [tcVNS] and ...
Francesca Proietti, Matteo Maria Ottaviani, Elisabetta Burchi, Giorgio Vivacqua, Gaia Anzini, Riccardo Antonio Ricciuti, Fioravante Capone, Vaughan G. Macefield, Vincenzo Di Lazzaro, Massimo Marano   +9 more
wiley   +1 more source

RRP12 Variants Are Associated With Autosomal Recessive Brain Calcifications

Movement Disorders, EarlyView.
Abstract Background Primary brain calcifications are observed in several inherited diseases due to different pathogenic mechanisms, including the disruption of the neurovascular unit, mitochondrial dysfunction, and impaired nucleic acid metabolism.
Edoardo Monfrini, Paola Rinchetti, Mathieu Anheim, Anna Klingseisen, Ouhaid Lagha‐Boukbiza, Zhidong Cen, Dehao Yang, Xinhui Chen, Reza Maroofian, Henry Houlden, Gioia Cappelletti, Anne‐Claire Richard, Olivier Quenez, Camilo Toro, Steven J. Frucht, Francesco Lotti, Wei Luo, David Hunt, Gael Nicolas, Giulietta M. Riboldi   +19 more
wiley   +1 more source

A Biomarker‐Based Classification of Corticobasal Syndrome

Movement Disorders, EarlyView.
Abstract Background Corticobasal syndrome (CBS) is a clinically defined syndrome with progressive movement and cortical dysfunction, caused by various underlying pathologies, most commonly tau‐predominant pathologies such as progressive supranuclear palsy and corticobasal degeneration, or Alzheimer's disease (AD).
Carla Palleis, Alexander Maximilian Bernhardt, Endy Weidinger, Urban M. Fietzek, Alexander Jäck, Sabrina Katzdobler, Johannes Gnörich, Theresa Bauer, Nicolai Franzmeier, Robert Perneczky, German Imaging Initiative for Tauopathies (GII4T), Matthias Brendel, Johannes Levin, Günter U. Höglinger   +13 more
wiley   +1 more source

The effect of exercise frequency on neuropathic pain and pain-related cellular reactions in the spinal cord and midbrain in a rat sciatic nerve injury model

, 2018
Megumi Sumizono, Harutoshi Sakakima, Shotaro Otsuka, Takuto Terashi, Kazuki Nakanishi, Koki Ueda, Seiya Takada, Kiyoshi Kikuchi   +7 more
openalex   +2 more sources

Failure to Mount Adaptive Responses to Stress Results in Dysregulation and Cell Death in the Midbrain Raphe [PDF]

, 2008
Jonathan G. McEuen, Sheryl G. Beck, Tracy L. Bale   +2 more
openalex   +1 more source

Biallelic Variants in SLC27A3 Cause a Complex Form of Neurodegeneration with Brain Iron Accumulation

Movement Disorders, EarlyView.
Abstract Background Complex lipid metabolism is one of the main biological pathways disrupted in neurodegeneration with brain iron accumulation (NBIA). SLC27A3 gene encodes for the very long‐chain acyl‐CoA synthetase 3, an acyl‐CoA ligase that activates long and very long‐chain fatty acids.
Lorena Travaglini, Cherim Jeon, Teresa Rizza, Antonio Novelli, Nicola Specchio, Anna Piluso, Enrico Bertini, Arcangela Iuso, Giacomo Garone   +8 more
wiley   +1 more source

BrainSTEM: A single-cell multiresolution fetal brain atlas reveals transcriptomic fidelity of human midbrain cultures. [PDF]

Sci Adv
Toh HSY, Xu L, Chen C, Yang P, Sun AX, Ouyang JF.   +5 more
europepmc   +1 more source