Results 211 to 220 of about 182,279 (337)

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Rotenone targets midbrain astrocytes to produce glial dysfunction-mediated dopaminergic neurodegeneration. [PDF]

Acta Neuropathol Commun
Miyazaki I, Isooka N, Kikuoka R, Imafuku F, Masai K, Tomimoto K, Sakaguchi M, Sogawa C, Sogawa N, Kitamura Y, Asanuma M.   +10 more
europepmc   +1 more source

Primary catastrophic antiphospholipid syndrome in children with midbrain infarction: a case report [PDF]

Qinghua Dong, Jianyun Yin, Hang Su, Qian Ni   +3 more
openalex   +1 more source

Dense cholinergic projections to auditory and multisensory nuclei of the intercollicular midbrain

, 2021
William A. Noftz, Nichole L. Beebe, Jeffrey G. Mellott, Brett R. Schofield   +3 more
openalex   +2 more sources

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Patterns of Longitudinal Regional Brain Atrophy in Patients With Different Progressive Supranuclear Palsy Clinical Variants. [PDF]

Neurology
Kumar M, Tosakulwong N, Weigand SD, Ali F, Stephens YC, Machulda MM, Schwarz CG, Senjem ML, Jack CR, Josephs KA, Whitwell JL.   +10 more
europepmc   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan, Christian Pifl, Thomas Steinkellner   +2 more
wiley   +1 more source

Supratentorial malignant lymphoma presenting with peduncular hallucination. [PDF]

Radiol Case Rep
Furuya C, Tsutsumi S, Hashizume A, Sugiyama N, Ueno H, Ishii H.   +5 more
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

The genetic architecture of brainstem structures. [PDF]

Nat Commun
Xue H, Fu J, Geng Z, Cheng J, Wang M, Zhang L, Cui G, Yu Y, Liao W, Zhang H, Gao B, Xu X, Han T, Yao Z, Zhang Q, Qin W, Liu F, Liang M, Wang S, Xu Q, Xu J, Wang C, Liu N, Ji Y, Zhang P, Li W, Wei W, Shi D, Lui S, Yan Z, Chen F, Zhang J, Shen W, Miao Y, Wang D, Gao JH, Yang Y, Xu K, Xian J, Zhang B, Zhang X, Zuo XN, Li MJ, Ye Z, Qiu S, Zhu W, Yu C, CHIMGEN Consortium.   +47 more
europepmc   +1 more source