NMDA receptors coordinate brain vascular development via neuron-to-endothelial tip cell crosstalk in zebrafish. [PDF]
Liu TT +13 more
europepmc +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
Iron Ions Increase the Thermal Stability In Vitro and Activity In Vivo of the 447R Mutant Form of Mouse Tryptophan Hydroxylase 2. [PDF]
Komleva PD +3 more
europepmc +1 more source
Altered Mechanical Properties of Astrocytes Lacking MLC1: Implications for the Leukodystrophy MLC
Mechanical properties of Mlc1‐null astrocytes are altered. Cytoskeleton‐related pathways are dysregulated in Mlc1‐null astrocytes. Mlc1‐null astrocytes show alterations in focal adhesions, which link the cytoskeleton to the extracellular matrix. ABSTRACT Loss of function of the astrocyte protein MLC1 causes Megalencephalic Leukoencephalopathy with ...
Quinty Bisseling +10 more
wiley +1 more source
The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degeneration. [PDF]
Kurniawan H +7 more
europepmc +1 more source
Scalable spokes pTx pulses for 2D turbo‐spin‐echo imaging at 7 T
Abstract Purpose Turbo spin echo (TSE) is important clinically. Unfortunately, 7 T TSE suffers from B1+‐induced signal dropouts. Magnitude‐based parallel transmit (pTx) pulse design algorithms cannot enforce phase patterns complying with the Carr‐Purcell‐Meiboom‐Gill conditions (90° phase shift between excitation and refocusing).
Minghao Zhang, Christopher T. Rodgers
wiley +1 more source
Artemisinin alleviates Parkinson's disease by targeting Adcy5-Gch1 axis to trigger a cascade generation of BH4 and dopamine in rats. [PDF]
Yang XX +5 more
europepmc +1 more source
Abstract Neuroanatomy studies in vertebrates have garnered significant attention in recent years, particularly driven by advancements in computerized tomography imaging techniques. Nonetheless, these advancements remain largely constrained to specific vertebrate groups, notably mammals, birds, and fish, leaving studies in reptiles at an incipient stage.
Giordanna Issa Lucas, Angele Martins
wiley +1 more source
Irisin inhibits dopaminergic neuron lactate metabolism and repairs mitochondrial function to alleviate Parkinson's disease by activating SIRT1 signaling pathway. [PDF]
Cai L +8 more
europepmc +1 more source

