Results 331 to 340 of about 212,558 (382)

Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck, Typhaine Dupont, Rupert Andrews Cavanagh, Olivier Postal, Jérôme Bourien, Jean‐Luc Puel, Nicolas Michalski, Boris Gourévitch   +7 more
wiley   +1 more source

Intranasal delivery of DPSC-derived small extracellular vesicles-encased phloroglucinol attenuates non-motor and motor deficits and promotes neurogenesis in an in vivo rat model of Parkinson's disease. [PDF]

Stem Cell Res Ther
Mondal K, Ghanty R, Mahadevan A, Waghmare G, Santhoshkumar R, Bn N, Datta I.   +6 more
europepmc   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, Volume 12, Issue 46, December 11, 2025.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

The cross-sectional associations between enlarged perivascular spaces and mild behavioral impairment in dementia-free older adults. [PDF]

J Alzheimers Dis
Mudalige D, Guan DX, McLeod GA, Smith EE, Ganesh A, Ismail Z.   +5 more
europepmc   +1 more source

Parkinson's disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss. [PDF]

Brain
Chemla A, Arena G, Sacripanti G, Barmpa K, Zagare A, Garcia P, Gorgogietas V, Antony P, Ohnmacht J, Baron A, Jung J, Lind-Holm Mogensen F, Michelucci A, Marzesco AM, Buttini M, Schmidt T, Grünewald A, Schwamborn JC, Krüger R, Saraiva C.   +19 more
europepmc   +1 more source

Osteopontin knockdown reverses HIV-induced cognitive deficits and influences motivation-related behavior. [PDF]

Brain Behav Immun
Loganathan S, Sun M, Lopez CA, Wangui J, Shirmamedova A, Johnson A, Louie P, Pelland Z, Alize-Hunt R, Zhu X, Smith D, Brown AM.   +11 more
europepmc   +1 more source

Acute Hemorrhagic Leukoencephalitis in Pregnancy. [PDF]

Neurohospitalist
Tuli A, Shaji A, Bhatia V, Balaini N, Pannu AK.   +4 more
europepmc   +1 more source

Multi-omics identifies microbiota-derived deoxycholic acid as a key mediator of blood-brain barrier dysfunction in Parkinson's disease. [PDF]

Imeta
Zhao Z, Chen J, Liu Y, Wang S, Zhao D, Bai C, Wu M, Hu G, Fu Y, Fang L, Liu X, Zhang Z, Zhan R, Zheng L, Yuan J.   +14 more
europepmc   +1 more source

Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms. [PDF]

World J Stem Cells
Jiang X, Lu ZM, Wang QL, Luo Y, Zhang J.
europepmc   +1 more source