Results 41 to 50 of about 471,464 (304)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
, 2016 International audienceThe plain of Saïss is a fertile area of great agricultural production with major economic interests. Therefore, the improved knowledge about the water supply is imperative within a context of recurrent droughts and overexploitation ...
Dauteuil, Olivier +2 more
core +3 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
V.—Ornithology of the Maroccan “Middle‐Atlas”
Ibis, 1920 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source
, 2011 This is the description of a Matlab script (classTAL.m) that automatically classifies BrainVoyager .voi maps with afni brain atlas.
Federico D'Agata, Federico D'Agata
core +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Swiss Journal of Palaeontology, 2023 Ever since the discovery of the first remains of Macrauchenia patachonica by Charles Darwin in 1834, this taxon has puzzled researchers with its peculiar anatomy.
Hans P. Püschel, Agustín G. Martinelli
doaj +1 more source
Atmospheric detectives: Atlas 2 teacher's guide with activities. For use with middle-school students [PDF]
, 1992 Can you imagine doing a science project in space? This is the challenging and exciting situation that researchers experience in Spacelab, the laboratory carried inside the Shuttle.
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source