Results 51 to 60 of about 122,580 (304)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Chemical, Mineralogical, and Biological Properties of Pistacia atlantica subsp. atlantica Essential Oils from the Middle Atlas of Morocco

Horticulturae
This study focused on Atlas pistachio (Pistacia atlantica subsp. atlantica), an endangered species from the Moroccan Middle Atlas, analyzing its leaves to assess their antioxidant and antimicrobial activity.
Mohammed Bassouya, Mohamed Chedadi, Mohamed El fadili, Jawhari Fatima Zahra, Younesse El-byari, Abdelaaty A. Shahat, Sonia Morya, Abdelfattah El Moussaoui, Mohammed Kara, Amina Bari   +9 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Middle Devonian ichnofossils from Hamar Laghdad (eastern Anti-Atlas, Morocco) [PDF]

Swiss Journal of Palaeontology
This article provides a description of the invertebrate trace fossils from the Hamar Laghdad region of Tafilalt in Morocco. These ichnoassemblages occur in Middle Devonian marly limestone layers, which are characterised by varying clastic content and ...
Wahiba Bel Haouz, Abdelouahed Lagnaoui, Christian Klug, Lahssen Baidder, Mehdi Maanan   +4 more
doaj   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The 5/95 gap in the indexation of psychiatric journals of low- and middle-income countries. [PDF]

, 2010
OBJECTIVE: To investigate the relationship between science production and the indexation level of low- and middle-income countries (LAMIC) journals in international databases.
Razzouk, D. [UNIFESP], Patel, V., Tyrer, P., Tyrer, P, Mari, JJ, Mari, J. J. [UNIFESP], Patel, V, Kieling, C, Herrman, H, Herrman, H., Razzouk, D, Kieling, C.   +11 more
core   +1 more source

New records of shore flies (Diptera, Ephydridae) from Morocco [PDF]

Journal of Insect Biodiversity and Systematics
Among the 45 collected and identified species, one genus (Scoliocephalus Becker, 1903) and nine species of shore flies (Diptera, Ephydridae) are recorded for the first time in Morocco of which seven species are new to the North African region ...
Rachida Akhrif, Khalid Aattouch, Mourad Beni-Eich, Paul L.Th. Beuk, Khadija Bouzrarf, Abdellatif Akarid, Boutaïna Belqat   +6 more
doaj  

Bordel de bled, bordel au Bled : figures rurales de la prostitution au Maroc

L’Année du Maghreb, 2010
Because too many shortcuts are taken in the study of female prostitution in the Middle Atlas, this article, taking us back to colonial and postcolonial times, will attempt to portray the phenomena in a different manner. By examining several recollections,
Mustapha Qadéry
doaj   +1 more source

A Parsed Linguistic Atlas of Early Middle English [PDF]

, 2019
This chapter reports on the construction of a new resource, the Parsed Linguistic Atlas of Early Middle English (PLAEME). Prose is underrepresented in the period 1250-1350, which is why this period is also underrepresented in the Penn Parsed Corpora of Historical English (PPCHE). This data gap is unfortunate, as we know that the period is important for
Robert Truswell, Rhona Alcorn, James Donaldson, Joel Wallenberg   +3 more
openaire   +1 more source