Results 141 to 150 of about 59,331 (203)

Cerebrovascular reactivity differences in healthy cerebral gray and white matter

Magnetic Resonance in Medicine, Volume 94, Issue 2, Page 745-753, August 2025.
Abstract Purpose To quantify the speed and magnitude of cerebrovascular reactivity (CVR) metrics in hemispheric gray and white matter. Methods A standardized isoxic hypercapnic cerebrovascular stimulus was administered using an automated arterial gas targeting system while monitoring blood oxygen–level dependent MRI.
Harrison T. Levine, Julien Poublanc, Ece Su Sayin, James Duffin, Olivia Sobczyk, Joseph A. Fisher, David J. Mikulis   +6 more
wiley   +1 more source

Cerebral Blood Flow and Glucose Metabolism of the Ischemic Rim in Spontaneously Hypertensive Stroke-Prone Rats with Occlusion of the Middle Cerebral Artery [PDF]

, 1995
H Kita, Katsuji Shima, Miwako Tatsumi, H Chigasaki   +3 more
openalex   +1 more source

Hybrid Multidelay PCASL Acquired With Time‐Encoded and Variable‐TR Schemes for the Assessment of Cerebral Perfusion in Moyamoya Disease

NMR in Biomedicine, Volume 38, Issue 7, July 2025.
Schematic drawings of the hybrid PCASL, consisting of four time‐encoded schemes with different timing settings, are shown. The entire LD/PLD is rearranged to show bolus dynamics. Actual multidelay images obtained with the hybrid scheme in a patient with moyamoya disease, along with his CBF and ATT maps, are shown.
Osamu Togao, Makoto Obara, Koji Yamashita, Kazufumi Kikuchi, Tatsuhiro Wada, Chiaki Tokunaga, Ryoji Mikayama, Koichi Arimura, Ataru Nishimura, Shota Ishida, Lena Václavů, Matthias J. P. van Osch, Kim van de Ven, Marc van Cauteren, Kousei Ishigami   +14 more
wiley   +1 more source

Effects of the Calcium Antagonist AE0047 on the Development of Neurological Deficit and Infarction after Middle Cerebral Artery Occlusion in Stroke-prone Spontaneously Hypertensive Rats [PDF]

, 1997
Hiroshi Shinyama, Tōru Kawamura, Minori Iwamoto, Yasuhiro Egi, Hideki Tanaka, Yoshiyasu Kawabata, Norifumi Nakamura, Yoshio Kagitani   +7 more
openalex   +1 more source

Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP‐CARE): A protocol for a randomized clinical trial

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
Abstract Background In patients resuscitated after cardiac arrest, a higher mean arterial pressure (MAP) may increase cerebral perfusion and attenuate hypoxic brain injury. Here we present the protocol of the mean arterial pressure after cardiac arrest and resuscitation (MAP‐CARE) trial aiming to investigate the influence of MAP targets on patient ...
V. H. Niemelä, M. Reinikainen, N. Nielsen, F. Bass, P. Young, G. Lilja, J. Dankiewicz, N. Hammond, J. Hästbacka, H. Levin, M. Moseby‐Knappe, M. Saxena, M. Tiainen, A. Ceric, J. Holgersson, C. B. Kamp, J. Tirkkonen, T. Oksanen, T. Kaakinen, S. Bendel, J. Düring, A. Lybeck, J. Johnsson, J. Unden, A. Lundin, J. Kåhlin, J. Grip, E. Lotman, L. Romundstad, P. Seidel, P. Stammet, T. Graf, A. Mengel, C. Leithner, J. Nee, P. Druwé, K. Ameloot, M. P. Wise, P. J. McGuigan, J. White, M. Govier, M. Maccaroni, M. Ostermann, P. Hopkins, A. Proudfoot, R. Handslip, D. Pogson, P. Jackson, A. Nichol, M. Haenggi, M. P. Hilty, M. Iten, C. Schrag, M. Nafi, M. Joannidis, C. Robba, T. Pellis, J. Belohlavek, D. Rob, Y. Arabi, S. Buabbas, C. Yew Woon, A. Aneman, A. Stewart, C. Arnott, M. Ramanan, R. Panwar, A. Delaney, M. Reade, B. Venkatesh, L. Navarra, B. Crichton, D. Knight, A. Williams, H. Friberg, T. Cronberg, J. C. Jakobsen, M. B. Skrifvars   +77 more
wiley   +1 more source

Specialized Pro‐Resolving Mediators as Emerging Players in Cardioprotection: From Inflammation Resolution to Therapeutic Potential

Acta Physiologica, Volume 241, Issue 7, July 2025.
ABSTRACT Aim Timely myocardial reperfusion is essential for restoring blood flow to post‐ischemic tissue, thereby reducing cardiac injury and limiting infarct size. However, this process can paradoxically result in additional, irreversible myocardial damage, known as myocardial ischemia–reperfusion injury (MIRI).
Anna De Bartolo, Naomi Romeo, Tommaso Angelone, Carmine Rocca   +3 more
wiley   +1 more source

Sensorimotor and cognitive consequences of middle cerebral artery occlusion in rats

, 1992
Carrie G. Markgraf, Edward J. Green, Barry E. Hurwitz, Eiharu Morikawa, W. Dalton Dietrich, Philip M. McCabe, Myron D. Ginsberg, Neil Schneiderman   +7 more
openalex   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, Volume 12, Issue 21, June 5, 2025.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, Volume 12, Issue 21, June 5, 2025.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

Positron Emission Tomographic Measurement of Acute Hemodynamic Changes in Primate Middle Cerebral Artery Occlusion

, 1992
Hiroshi Tenjin, Satoshi Ueda, Norihiko Mizukawa, Yoshio Imahori, Akihiko HINO, Yoshio Ohmori, Kiyoshi YASUKOCHI, Hisamitsu Nakahashi, Kazuo Wakita, Hitoshi Horii, Ryou Fujii   +10 more
openalex   +2 more sources