Results 181 to 190 of about 59,331 (203)
Critical Role of Skin in Pathogenesis: Bidirectional Crosstalk Between Skin and Multiple Organs
MedComm – Future Medicine, Volume 4, Issue 2, June 2025.The skin functions as both a protective barrier and an autonomous immune organ, maintaining dynamic interactions with internal organs. This review analyzes skin‐organ crosstalk mechanisms, highlighting key cytokines (particularly IL‐17A) and microbial metabolites that mediate interorgan communication.
Wende Deng +7 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 45, Issue 2, June 2025.Trimethyltin (TMT) induces transient neuronal loss and cognitive impairments, serving as a model for transient brain damage. This study investigated the effects of early memantine (MEM) treatment on TMT‐induced brain injury. Memantine worsened TMT‐induced cognitive impairment and neuronal degeneration in the hippocampus, suggesting that early MEM ...
Yusuke Onaka +4 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong +6 more
wiley +1 more source
Restoration of Glymphatic Influx After Photothrombotic Stroke Using Low‐Intensity Focused Ultrasound
CNS Neuroscience &Therapeutics, Volume 31, Issue 6, June 2025.We examine immediate effect and 7‐day LIFU on CSF influx in stroke mice. LIFU rapidly increased CSF influx, peaking at 20–30 min post‐stimulation. Stroke reduced CSF influx, lowest at day 1‐3, with recovery by day 7. Daily contralesional LIFU restored CSF influx, suggesting stroke recovery benefits.
Ming‐Yen Hsiao +5 more
wiley +1 more source
Intra‐Arterial Deoxyribonuclease Therapy Improves Stroke Outcomes in Aged Mice
CNS Neuroscience &Therapeutics, Volume 31, Issue 6, June 2025.We explored a novel direct intra‐arterial DNase therapy and its effect in aged mice with AIS. IA DNase therapy decreased neutrophil and NET burden in the penumbra in aged mice with AIS, provided more efficient cerebral reperfusion, and better functional outcomes after recanalization during the treatment of stroke.
Junxiang Yin +5 more
wiley +1 more source