Results 201 to 210 of about 71,608 (264)

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Efficacy and safety of mechanical thrombectomy in distal medium middle cerebral artery occlusion ischemic stroke patients on low-dose aspirin. [PDF]

open access: yesInt J Stroke
Salim HA   +62 more
europepmc   +1 more source

Cardiogenic cerebral infarction after Takotsubo cardiomyopathy in a patient with catatonia: A case report

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background Takotsubo cardiomyopathy (TTC) is a transient cardiac condition often triggered by an emotional or physical stress. TTC usually has a benign clinical course with full recovery. However, in rare cases, TTC is complicated by cardiogenic shock, left ventricular rupture, or ventricular thrombus.
Masaki Fujiwara   +4 more
wiley   +1 more source

Acute middle cerebral artery occlusion due to a small internal carotid aneurysm cavity with blood stagnation: illustrative case. [PDF]

open access: yesJ Neurosurg Case Lessons
Uezato M   +7 more
europepmc   +1 more source

Sialylation patterns in cerebral amyloid angiopathy

open access: yesBrain Pathology, Volume 36, Issue 2, March 2026.
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau   +8 more
wiley   +1 more source

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo   +5 more
wiley   +1 more source

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