Results 91 to 100 of about 3,362,044 (295)

A promessa da ?inserção profissional instigante? da sociedade em rede: a imposição de sentido e a sua sociologia

open access: yesDados: Revista de Ciências Sociais, 2003
The article examines some of the consequences of the ways by which the contemporary Social Sciences deal with the notion of "network society". Based on the differences in perspective between French and Anglo-Saxon authors, we first discuss the problem of
Grün Roberto
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Trends and Patterns in Consumption Expenditure: A Review of Class and Rural-Urban Disparities [PDF]

open access: yes
This paper primarily aims to capture the changing patterns of consumption expenditure of three broad classes, namely, the ‘upper’ ‘middle’ and ‘bottom’ classes in the rural and urban India.
Roy, Satyaki
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

L’emploi associatif et la reproduction des couches moyennes salariées

open access: yesSociologies, 2011
Annual surveys carried out by a French statistical institute between 1993 and 2002 show an increasing proportion of at least 25 years old university graduates in non-profit sector.
Gérard Chevalier
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

HOW IS THE EUROPEAN UNION SECURITIZING CLIMATE CHANGE IN THE MIDDLE EAST? [PDF]

open access: yes
This thesis examines the complex relationship between climate change and regional instability in the Middle East and North Africa (MENA), by focusing on Syria, and assesses the European Union's approach to this nexus.
Furtun, Şakire
core  

The Middle Class is Us: Measuring Indonesian Middle Class [PDF]

open access: yesProceedings of the 2nd International Conference on Indonesian Economy and Development (ICIED 2017), 2018
Turro S. Wongkaren, Ketut Krisna
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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