Results 91 to 100 of about 3,362,044 (295)
The article examines some of the consequences of the ways by which the contemporary Social Sciences deal with the notion of "network society". Based on the differences in perspective between French and Anglo-Saxon authors, we first discuss the problem of
Grün Roberto
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Trends and Patterns in Consumption Expenditure: A Review of Class and Rural-Urban Disparities [PDF]
This paper primarily aims to capture the changing patterns of consumption expenditure of three broad classes, namely, the ‘upper’ ‘middle’ and ‘bottom’ classes in the rural and urban India.
Roy, Satyaki
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
L’emploi associatif et la reproduction des couches moyennes salariées
Annual surveys carried out by a French statistical institute between 1993 and 2002 show an increasing proportion of at least 25 years old university graduates in non-profit sector.
Gérard Chevalier
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
HOW IS THE EUROPEAN UNION SECURITIZING CLIMATE CHANGE IN THE MIDDLE EAST? [PDF]
This thesis examines the complex relationship between climate change and regional instability in the Middle East and North Africa (MENA), by focusing on Syria, and assesses the European Union's approach to this nexus.
Furtun, Şakire
core
The Middle Class is Us: Measuring Indonesian Middle Class [PDF]
Turro S. Wongkaren, Ketut Krisna
openaire +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

