Results 61 to 70 of about 2,985,063 (347)

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

European-Israeli Military Relations during Israel Regional Wars (2006-2016)

open access: yesTürkiye Ortadoğu Çalışmaları Dergisi, 2020
The study aims to answer the question of the nature of European-Israeli military relations during the period of four wars, particularly in the Middle East region with Israel; one battle with the Lebanese Hezbollah, and three wars on the Gaza Strip.
Mohammed Abu Saada, Yıldırım Turan
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Burnout among healthcare providers in the complex environment of the Middle East: a systematic review

open access: yesBMC Public Health, 2019
Burnout is a syndrome characterized by emotional exhaustion, increased depersonalization, and a diminished sense of personal accomplishment due to chronic emotional stress at work.
Z. Chemali   +7 more
semanticscholar   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Araştırma Görevlilerinin Bilim ve Bilimsel Etkinliklere İlişkin Algılarının Karşılaştırmalı Analizi

open access: yesAnkara Üniversitesi Eğitim Bilimleri Fakültesi Dergisi, 2014
Bu nicel çalışmada araştırma görevlilerinin bilime ve bilimsel etkinliklere ilişkin algıları araştırılmıştır. Daha ayrıntılı olarak bu çalışmada araştırma görevlilerinin bilim ve bilimsel etkinlikler hakkındaki görüşleri araştırma görevliliği statüsü (
Nuri KARA   +3 more
doaj  

Middle East respiratory syndrome coronavirus (MERS-CoV): A review.

open access: yesGERMS, 2019
As a novel coronavirus first reported by Saudi Arabia in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) is responsible for an acute human respiratory syndrome.
N. Ramadan, H. Shaib
semanticscholar   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Middle East respiratory syndrome coronavirus (MERS-CoV)

open access: yesSaudi Medical Journal, 2017
Coronavirus memiliki famili besar yang menyebabkan penyakit pada manusia dan hewan. Pada manusia dapat menyebabkan penyakit dengan gejala mulai dari common cold sampai Severe Acute Respiratory Syndrome (SARS)
D. Murniati
semanticscholar   +1 more source

Genetic diversity and population structure of the Taigan dog breed

open access: yesFEBS Open Bio, EarlyView.
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova   +10 more
wiley   +1 more source

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