Results 91 to 100 of about 57,763 (248)

Middle East Respiratory Syndrome Coronavirus Patients in the ICU [PDF]

Journal of Intensive Care Medicine, 2015
The recent report on ‘‘Middle East Respiratory Syndrome Coronavirus Patients in ICU’’ is very interesting. AlHameed et al concluded that ‘‘Middle East respiratory syndrome coronavirus carries a high mortality rate in patients who require ICU admission, with a significant number of patients developing Multiorgan System Failure (MOSF) (p.
openaire   +3 more sources

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): State of the Science

Microorganisms, 2020
Coronaviruses belong to a large family of viruses that can cause disease outbreaks ranging from the common cold to acute respiratory syndrome. Since 2003, three zoonotic members of this family evolved to cross species barriers infecting humans and ...
Ahmed Mostafa, Ahmed Kandeil, Mahmoud Shehata, Rabeh El Shesheny, Abdallah M. Samy, Ghazi Kayali, Mohamed A. Ali   +6 more
doaj   +1 more source

Impact of Suaahara, an at‐scale multisectoral nutrition programme, on health workers' maternal and child health, and nutrition knowledge and skills in Nepal

Maternal &Child Nutrition, EarlyView.
Suaahara improved nutrition‐related skills among health facility workers and Female Community Health Volunteers, particularly in measuring the weight of children and pregnant women, assessing the height/length of children, monitoring and promoting growth, and identifying malnourished children.
Deependra K. Thapa, Edward A. Frongillo, Shalini Suresh, Ramesh P. Adhikari, Bhim Pun, Karuna L. Shakya, Raj Mandal, Subir K. Kole, Kenda Cunningham   +8 more
wiley   +1 more source

Middle East Respiratory Syndrome Coronavirus Disease in Children

Pediatric Infectious Disease Journal, 2014
In the initial description of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, many affected patients were adults with underlying medical comorbidities. Data on the clinical presentation and outcome of pediatric cases are lacking.
Rafat F. Alhakeem, Abdullah M. Assiri, Sarah Alsubaie, Sami Al Hajjar, Ali Albarrak, Hesham Flemban, Hatem Q. Makhdoom, Jaffar A. Al-Tawfiq, Jaffar A. Al-Tawfiq, Fahad Alrabiah, Abdullah A Al-Rabeeah, Ziad A. Memish   +11 more
openaire   +4 more sources

Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4

Journal of Infectious Diseases, 2015
Middle East respiratory syndrome coronavirus (MERS-CoV) causes life-threatening disease. Dipeptidyl peptidase 4 (DPP4) is the receptor for cell binding and entry.
Kun Li, C. Wohlford-Lenane, S. Perlman, Jincun Zhao, Alexander K Jewell, Leah R Reznikov, K. Gibson-Corley, D. Meyerholz, P. McCray   +8 more
semanticscholar   +1 more source

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim, Andy Cano Tran, Ju Kim, Humblenoble Stembridge Ayuk, Adam Sparrow, Lorenzo Bossi, Megan Brown, Emil Joseph Vergara, Kathrin Göritzer, Elisabetta Groppelli, Tae‐Ho Kwon, Julian K. C. Ma, Yong‐Suk Jang, Rajko Reljic   +13 more
wiley   +1 more source

A database of geopositioned Middle East Respiratory Syndrome Coronavirus occurrences [PDF]

Scientific Data, 2019
AbstractAs a World Health Organization Research and Development Blueprint priority pathogen, there is a need to better understand the geographic distribution of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and its potential to infect mammals and humans.
Rebecca R.E. Ramshaw, Julia Hon, Shreya Shirude, David M. Pigott, David M. Pigott, Joshua C. P. Osborne, Amy Y. Hong, Ian D. Letourneau, Simon I. Hay, Simon I. Hay, Julia D. Morgan, Maria D. Van Kerkhove   +11 more
openaire   +3 more sources

Association between Severity of MERS-CoV Infection and Incubation Period

Emerging Infectious Diseases, 2016
We analyzed data for 170 patients in South Korea who had laboratory-confirmed infection with Middle East respiratory syndrome coronavirus. A longer incubation period was associated with a reduction in the risk for death (adjusted odds ratio/1-day ...
Victor Virlogeux, Minah Park, Joseph T. Wu, Benjamin J. Cowling   +3 more
doaj   +1 more source

Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

Journal of Infectious Diseases, 2015
Middle East respiratory syndrome (MERS) is associated with a mortality rate of >35%. We previously showed that MERS coronavirus (MERS-CoV) could infect human macrophages and dendritic cells and induce cytokine dysregulation. Here, we further investigated
Hin Chu, Jie Zhou, Bosco Ho-Yin Wong, Cun Li, J. Chan, Zhongshan Cheng, Dong Yang, Dong Wang, A. Lee, Chuangen Li, M. Yeung, Jian-Piao Cai, I. Chan, W. Ho, K. To, B. Zheng, Yanfeng Yao, C. Qin, K. Yuen   +18 more
semanticscholar   +1 more source

Determinants of Crowdsourcing Openness in High‐Urgency Conditions: A Configurational Approach

R&D Management, EarlyView.
ABSTRACT Managers increasingly use crowdsourcing to address problems in high‐urgency conditions. However, to maximize its benefits, they must determine the appropriate level of openness of crowdsourcing challenges—openness in knowledge sourcing and openness in knowledge use.
Annalisa Caloffi, Ana Colovic, Federica Rossi, Jiachen Yang, Mehdi Bagherzadeh   +4 more
wiley   +1 more source