Results 71 to 80 of about 66,034 (171)

Antibodies and vaccines against Middle East respiratory syndrome coronavirus

Emerging Microbes and Infections, 2019
The Middle East respiratory syndrome coronavirus (MERS-CoV) has spread through 27 countries and infected more than 2,200 people since its first outbreak in Saudi Arabia in 2012.
Jiuyang Xu, Wenxu Jia, Pengfei Wang, Senyan Zhang, Xuanling Shi, Xinquan Wang, Linqi Zhang   +6 more
doaj   +1 more source

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): State of the Science

Microorganisms, 2020
Coronaviruses belong to a large family of viruses that can cause disease outbreaks ranging from the common cold to acute respiratory syndrome. Since 2003, three zoonotic members of this family evolved to cross species barriers infecting humans and ...
Ahmed Mostafa, Ahmed Kandeil, Mahmoud Shehata, Rabeh El Shesheny, Abdallah M. Samy, Ghazi Kayali, Mohamed A. Ali   +6 more
doaj   +1 more source

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

Advanced Healthcare Materials, Volume 15, Issue 26, 10 July 2026.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao, Akhila Naru, Dhanush Gandavadi, Mengxi Zheng, Saraswathi Lanka, Hyeongjun Cho, Chau Nguyen Minh Hoang, Jianqiang Zhang, Ying Fang, Xing Wang   +9 more
wiley   +1 more source

Middle East Respiratory Syndrome Coronavirus Patients in the ICU [PDF]

Journal of Intensive Care Medicine, 2015
The recent report on ‘‘Middle East Respiratory Syndrome Coronavirus Patients in ICU’’ is very interesting. AlHameed et al concluded that ‘‘Middle East respiratory syndrome coronavirus carries a high mortality rate in patients who require ICU admission, with a significant number of patients developing Multiorgan System Failure (MOSF) (p.
openaire   +2 more sources

Proficiency testing for the detection of Middle East respiratory syndrome coronavirus demonstrates global capacity to detect Middle East respiratory syndrome coronavirus [PDF]

Journal of Medical Virology, 2018
The first reported case of Middle East respiratory syndrome coronavirus (MERS‐CoV) infection was identified in Saudi Arabia in September 2012, since which time there have been over 2000 laboratory‐confirmed cases, including 750 deaths in 27 countries. Nucleic acid testing (NAT) is the preferred method for the detection of MERS‐CoV.
Torsten Theis, Katherine A. Lau, Joanna L. Gray, Christopher J. Oxenford, Gregory J. Walker, William D. Rawlinson   +5 more
openaire   +2 more sources

p‐Sulfonatocalix[4]arene‐Based Ratiometric Fluorescence Chemosensor Array for the Differential Detection of Polycationic Peptides

ChemistryEurope, Volume 4, Issue 7, July 2026.
A ratiometric fluorescence chemosensor array based on pyrene‐functionalized calixarenes enables complexation‐induced aggregation sensing of polycationic peptides in water. The system discriminates closely related sequences differing by minimal arginine content, including biologically relevant coronavirus spike protein cleavage‐site motifs, highlighting
Joana N. Martins, Márcia Pessêgo, Lucia Méndez‐Gómez, Hanieh Mahmoodi, Javier Montenegro, Luis Garcia‐Rio, João Carlos Lima, Nuno Basílio   +7 more
wiley   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

Modulation of the immune response by Middle East respiratory syndrome coronavirus [PDF]

Journal of Cellular Physiology, 2018
AbstractCoronavirus (CoV) infections are commonly associated with respiratory and enteric disease in humans and animals. In 2012, a new human disease called Middle East respiratory syndrome (MERS) emerged in the Middle East. MERS was caused by a virus that was originally called human coronavirus‐Erasmus Medical Center/2012 but was later renamed as ...
Somayeh Shokri, Shahab Mahmoudvand, Reza Taherkhani, Fatemeh Farshadpour   +3 more
openaire   +2 more sources

The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors

Protein Science, Volume 35, Issue 7, July 2026.
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley   +1 more source

Development and Physicochemical Stability of an Oral GS‐441524 Suspension for Weight‐Adjusted Treatment of Feline Infectious Peritonitis

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
A 50 mg/mL oral GS‑441524 suspension for feline infectious peritonitis (FIP) was developed and shown to remain physico‐chemically stable for at least 12 weeks under tested storage conditions and 28 days in‑use, supporting accurate weight‑adjusted dosing as an extemporaneously compounded formulation under veterinary supervision.
Cédric Wernli, Ursula Streit
wiley   +1 more source