Results 91 to 100 of about 94,297 (215)

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

The Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu, Asish Dasgupta, Jaskaran Singh Hora, Kuang‐Hueih Chen, Arinjay Banerjee, Stephen L. Archer   +5 more
wiley   +1 more source

Middle East respiratory syndrome (MERS) coronavirus and dromedaries

The Veterinary Journal, 2017
Middle East Respiratory Syndrome (MERS) is a zoonotic viral disease that can be transmitted from dromedaries to human beings. More than 1500 cases of MERS have been reported in human beings to date. Although MERS has been associated with 30% case fatality in human beings, MERS coronavirus (MERS-CoV) infection in dromedaries is usually asymptomatic.
Wernery, U, Lau, SKP, Woo, PCY
openaire   +4 more sources

COVID-19 Infection: Implications for Perioperative and Critical Care Physicians. [PDF]

, 2020
Healthcare systems worldwide are responding to Coronavirus Disease 2019 (COVID-19), an emerging infectious syndrome caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. Patients with COVID-19 can progress from asymptomatic or
Greenland, John R, London, Martin J, Michelow, Marilyn D, Wang, Linlin   +3 more
core  

Middle East Respiratory Syndrome Coronavirus, Saudi Arabia, 2017–2018

Emerging Infectious Diseases, 2019
We characterized exposures and demographics of Middle East respiratory syndrome coronavirus cases reported to the Saudi Arabia Ministry of Health during July 1–October 31, 2017, and June 1–September 16, 2018.
Ahmed Hakawi, Erica Billig Rose, Holly M. Biggs, Xiaoyan Lu, Mutaz Mohammed, Osman Abdalla, Glen R. Abedi, Ali A. Alsharef, Aref Ali Alamri, Samar Ahmad Bereagesh, Kamel M. Al Dosari, Saad Abdullah Ashehri, Waad Ghassan Fakhouri, Saleh Zaid Alzaid, Stephen Lindstrom, Susan I. Gerber, Abdullah Asiri, Hani Jokhdar, John T. Watson   +18 more
doaj   +1 more source

Contemporary disasters may not kill more women than men: an empirical inquiry into sex‐differentiated fatalities in the twenty‐first century

Disasters, Volume 50, Issue 3, July 2026.
Abstract This study investigates the claim that women are disproportionately more likely to die in disasters by reviewing existing data sources and compiling new datasets on sex‐differentiated disaster fatalities in the twenty‐first century. The analysis is structured by disaster type, covering geophysical, meteorological, climatological, hydrological,
Olivier Rubin
wiley   +1 more source

Antibodies and vaccines against Middle East respiratory syndrome coronavirus

Emerging Microbes and Infections, 2019
The Middle East respiratory syndrome coronavirus (MERS-CoV) has spread through 27 countries and infected more than 2,200 people since its first outbreak in Saudi Arabia in 2012.
Jiuyang Xu, Wenxu Jia, Pengfei Wang, Senyan Zhang, Xuanling Shi, Xinquan Wang, Linqi Zhang   +6 more
doaj   +1 more source

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): State of the Science

Microorganisms, 2020
Coronaviruses belong to a large family of viruses that can cause disease outbreaks ranging from the common cold to acute respiratory syndrome. Since 2003, three zoonotic members of this family evolved to cross species barriers infecting humans and ...
Ahmed Mostafa, Ahmed Kandeil, Mahmoud Shehata, Rabeh El Shesheny, Abdallah M. Samy, Ghazi Kayali, Mohamed A. Ali   +6 more
doaj   +1 more source

Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq, Doni Dermawan, Samir Chtita   +2 more
wiley   +1 more source

Predicting SARS‐CoV‐2 Infection With Graph Attention Capsule Networks

Computational Intelligence, Volume 42, Issue 3, June 2026.
ABSTRACT Recent studies in machine learning have demonstrated the effectiveness of applying graph neural networks (GNNs) to single‐cell RNA sequencing (scRNA‐seq) data to predict COVID‐19 disease states. In this study, we propose an explainable graph attention capsule network (GACapNet), which extracts and fuses Severe Acute Respiratory Syndrome ...
Runjie Zhu, Jimmy Xiangji Huang, Amran Bhuiyan, Zhiwen Xie, Guangyou Zhou   +4 more
wiley   +1 more source

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, Volume 21, Issue 5, Page 495-505, May 2026.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source