Results 61 to 70 of about 5,451,452 (199)

Reverse transcription recombinase polymerase amplification assay for the detection of middle East respiratory syndrome coronavirus [PDF]

, 2013
The emergence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in the eastern Mediterranean and imported cases to Europe has alerted public health authorities.
El Wahed, Ahmed Abd, Weidmann, Manfred, Wahed, Ahmed Abd El, Hufert, Frank T, Heidenreich, Doris, Abd El Wahed, Ahmed, Patel, Pranav, Hufert, Frank T.   +7 more
core   +1 more source

Characterization of Immune Responses to RBD‐SD1 Nanoparticle Vaccines Derived From ACE2‐Capable HKU5‐CoV‐2, NeoCoV, and HKU5 Merbecoviruses

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles presenting HKU5, NeoCoV, and HKU5‐CoV‐2 RBD‐SD1 induced strong, cross‐reactive IgG responses in immunized mice. The surrogate virus neutralization test demonstrated strong activity in sera from homologous vaccination. ABSTRACT Recent discoveries of merbecoviruses such as HKU5, NeoCoV, and HKU5‐CoV‐2 that use angiotensin ...
Peter J. Halfmann, Jeong Soo Lee, Augustine Duffy, Tong Wang, Bingcheng Huang, James Z. Kurdi, Ajay Inampudi, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +11 more
wiley   +1 more source

Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea

Emerging Infectious Diseases, 2015
We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests.
Wan Beom Park, Ranawaka A.P.M. Perera, Pyoeng Gyun Choe, Eric H.Y. Lau, Seong Jin Choi, June Young Chun, Hong Sang Oh, Kyoung-Ho Song, Ji Hwan Bang, Eu Suk Kim, Hong Bin Kim, Sang Won Park, Nam Joong Kim, Leo Lit Man Poon, Ghazi Kayali, Myoung-don Oh   +15 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Common adverse events associated with the use of ribavirin for severe acute respiratory syndrome in Canada [PDF]

, 2003
Although information on efficacy and adverse drug reactions is lacking, ribavirin has been used empirically for the treatment of severe acute respiratory syndrome (SARS). We report common adverse events in 110 patients with suspected or probable SARS who
Dresser, L., Linda Dresser, Larissa Matukas, Elizabeth J. Phillips, Phillips, E.J., Matukas, L., Sandra R. Knowles, Knowles, S.R.   +7 more
core   +1 more source

Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus [PDF]

Emerging Infectious Diseases, 2019
Middle East respiratory syndrome coronavirus (MERS-CoV) was detected in humans in 2012. Since then, sporadic outbreaks with primary transmission through dromedary camels to humans and outbreaks in healthcare settings have shown that MERS-CoV continues to pose a threat to human health.
Harvey, Ruth, Mattiuzzo, Giada, Hassall, Mark, Sieberg, Andrea, Müller, Marcel A., Drosten, Christian, Rigsby, Peter, Caly, L., Li, C., Zhao, L., Tan, W., Peiris, M., Perera, M., Kang, C., Wang, J. S., Haagmans, B., Okba, N. M.A., Gopal, R., Myhill, S., Thornburg, N.   +19 more
openaire   +4 more sources

The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”

Journal of the Formosan Medical Association, 2013
A novel lineage C betacoronavirus, originally named human coronavirus EMC/2012 (HCoV-EMC) and recently renamed Middle East respiratory syndrome coronavirus (MERS-CoV), that is phylogenetically closely related to Tylonycteris bat coronavirus HKU4 and ...
Jasper Fuk-Woo Chan, Susanna Kar-Pui Lau, Patrick Chiu-Yat Woo   +2 more
doaj   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Middle East Respiratory Syndrome Coronavirus Patients in the ICU [PDF]

Journal of Intensive Care Medicine, 2015
The recent report on ‘‘Middle East Respiratory Syndrome Coronavirus Patients in ICU’’ is very interesting. AlHameed et al concluded that ‘‘Middle East respiratory syndrome coronavirus carries a high mortality rate in patients who require ICU admission, with a significant number of patients developing Multiorgan System Failure (MOSF) (p.
openaire   +2 more sources

Asymptomatic Middle East Respiratory Syndrome Coronavirus Infection in Rabbits [PDF]

Journal of Virology, 2015
ABSTRACT The ability of Middle East respiratory syndrome coronavirus (MERS-CoV) to infect small animal species may be restricted given the fact that mice, ferrets, and hamsters were shown to resist MERS-CoV infection. We inoculated rabbits with MERS-CoV.
Haagmans, Bart L, van den Brand, Judith M A, Provacia, Lisette B, Raj, V Stalin, Stittelaar, Koert J, Getu, Sarah, de Waal, Leon, Bestebroer, Theo M, Amerongen, Geert van, Verjans, Georges M G M, Fouchier, Ron A M, Smits, Saskia L., Kuiken, Thijs, Osterhaus, Albert D M E   +13 more
openaire   +3 more sources