Results 61 to 70 of about 57,763 (248)

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

The impact of COVID‐19 on public perceptions of wild meat in Central Africa

People and Nature, EarlyView.
Abstract Wild meat is a significant source of food and income generation in Central Africa. However, there is little knowledge of how the assumed link between COVID‐19 and wild meat consumption has been discussed by the media and received by the public. In this study, we conducted media content analysis of 264 articles published in 2019–2020 related to
Yuhan Li, Lude Kinzonzi, Paul Loundou, Divin Malekani, Krossy Mavakala, Christian Mikolo Yobo, Katharine Abernethy, Matilda Eve Dunn, Donald Midoko Iponga, Robert Mwinyihali, Joss Wright, Eleanor Jane Milner‐Gulland, Lauren Coad, Juliet H. Wright, Daniel W. S. Challender   +14 more
wiley   +1 more source

Asymptomatic Middle East Respiratory Syndrome Coronavirus Infection in Rabbits [PDF]

Journal of Virology, 2015
ABSTRACT The ability of Middle East respiratory syndrome coronavirus (MERS-CoV) to infect small animal species may be restricted given the fact that mice, ferrets, and hamsters were shown to resist MERS-CoV infection. We inoculated rabbits with MERS-CoV.
Haagmans, Bart L, van den Brand, Judith M A, Provacia, Lisette B, Raj, V Stalin, Stittelaar, Koert J, Getu, Sarah, de Waal, Leon, Bestebroer, Theo M, Amerongen, Geert van, Verjans, Georges M G M, Fouchier, Ron A M, Smits, Saskia L., Kuiken, Thijs, Osterhaus, Albert D M E   +13 more
openaire   +3 more sources

The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”

Journal of the Formosan Medical Association, 2013
A novel lineage C betacoronavirus, originally named human coronavirus EMC/2012 (HCoV-EMC) and recently renamed Middle East respiratory syndrome coronavirus (MERS-CoV), that is phylogenetically closely related to Tylonycteris bat coronavirus HKU4 and ...
Jasper Fuk-Woo Chan, Susanna Kar-Pui Lau, Patrick Chiu-Yat Woo   +2 more
doaj   +1 more source

Middle East Respiratory Syndrome Coronavirus epidemic impact on healthcare workers' risk perceptions, work and personal lives.

Journal of Infection in Developing Countries, 2019
INTRODUCTION Middle East respiratory syndrome coronavirus (MERS-CoV) continues to cause frequent outbreaks in hospitals in Saudi Arabia. Since healthcare workers (HCWs) have a higher risk of acquiring and spreading MERS-CoV, we aimed to evaluate the ...
S. Alsubaie, Mohamad Hani Temsah, A. Al-Eyadhy, Ibrahim Gossady, G. Hasan, Abdulkarim Al-rabiaah, A. Jamal, A. Alhaboob, F. Alsohime, A. Somily   +9 more
semanticscholar   +1 more source

Introduction to the database “efficacy of different treatment modalities for lower respiratory tract infections in children”

Pediatric Discovery, EarlyView.
This article introduces a national, multicenter, prospective, non‐interventional, observational registry study, which established a comprehensive and sustainable database of lower respiratory tract infection in children. This database will help improve the scientific research efficiency of clinicians and facilitate the exploration of underlying ...
Yu Deng, Bing Hu, Yingxue Zou, Zhengxiu Luo, Guangli Zhang, Jinhai Ma, Changshan Liu, Xiaoyan Dong, Huifen Zi, Chuangli Hao, Rongjun Lin, Xiangrong Zheng, Bingfei Li, Fenhua Chen, Mei Fang, Weimin Tian, Zhiqiang Zhuo, Deyu Zhao, Zhimin Chen, Yuejie Zheng, Jingyang Zheng, Yong Yin, Qiuyu Tang, Liqun Wu, Li Gu, Jinzhun Wu, Liyi He, Tao Ai, Ning Wang, Minjun Zhang, Hailin Zhang, Hanmin Liu, Youxiang Zhang, Jianguo Hong, Zhiying Han, Yunbo Mo, Hongmei Qiao, Zhiliang Tian, Zengni Li, Quan Lu, Enmei Liu   +40 more
wiley   +1 more source

Lack of Middle East Respiratory Syndrome Coronavirus Transmission in Rabbits [PDF]

Viruses, 2019
Middle East respiratory syndrome coronavirus (MERS-CoV) transmission from dromedaries to humans has resulted in major outbreaks in the Middle East. Although some other livestock animal species have been shown to be susceptible to MERS-CoV, it is not fully understood why the spread of the virus in these animal species has not been observed in the field.
W. Widagdo, Nisreen M. A. Okba, Mathilde Richard, Dennis de Meulder, Theo M. Bestebroer, Pascal Lexmond, Elmoubasher A. B. A. Farag, Mohammed Al-Hajri, Koert J. Stittelaar, Leon de Waal, Geert van Amerongen, Judith M. A. van den Brand, Bart L. Haagmans, Sander Herfst   +13 more
openaire   +5 more sources

Weathering the storms of climate change: Preparing persons with disabilities and the physiatrists who provide their care for extreme hurricanes

PM&R, EarlyView.
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae, James M. Shultz, J. Marshall Shepherd, Zelde Espinel, Lauren T. Shapiro   +4 more
wiley   +1 more source

Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)

Journal of Biological Chemistry, 2016
Ebola virus infection can cause severe hemorrhagic fever with a high mortality in humans. The outbreaks of Ebola viruses in 2014 represented the most serious Ebola epidemics in history and greatly threatened public health worldwide.
Nan Zhou, T. Pan, Junsong Zhang, Qianwen Li, Xue Zhang, C. Bai, F. Huang, T. Peng, Jianhua Zhang, Chao Liu, L. Tao, Hui Zhang   +11 more
semanticscholar   +1 more source

Middle East Respiratory Syndrome Coronavirus Outbreaks

, 2023
Middle East respiratory syndrome coronavirus (MERS-CoV) is a single-stranded RNA-enveloped virus that belongs to the Coronaviridae family. Initially reported in 2012 in Saudi Arabia, MERS-CoV is a zoonotic virus originating from bats and transmitted from camels to humans and among humans by contact.
F., Alhetheel, Abdulkarim, A., hetheel, Faisal   +1 more
openaire   +2 more sources