Results 101 to 110 of about 2,650,610 (297)

THE MODEL FOR ASSESSMENT THE RELIABILITY OF STRUCTURES IN VIRTUALIZED DATA CENTERS

open access: yesInformation and Telecommunication Sciences, 2015
In this paper has been proposed model of communication system with dynamic network topology in which the process of changing the topology graph over time is to create or break connections between components within a single physical server or between ...
Mykhailo M. Klymash   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Features of processing of marine seismic observations using finite-difference full-wave migration

open access: yesГеофизический журнал, 2013
Features and basic principles of plotting the graph of marine seismic observations processing with application of original method of finite-difference total wave migration of the sum of central middle point, which is more stabile in case of investigation
A. O. Verpahovskaya   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Tits alternatives for graph products

open access: yes, 2015
We discuss various types of Tits Alternative for subgroups of graph products of groups, and prove that, under some natural conditions, a graph product of groups satisfies a given form of Tits Alternative if and only if each vertex group satisfies this ...
Antolin, Yago, Minasyan, Ashot
core   +1 more source

Graph Equations for Line Graphs, Jump Graphs, Middle Graphs, Splitting Graphs And Line Splitting Graphs

open access: yesMapana - Journal of Sciences, 2010
For a graph G, let G, L(G), J(G) S(G), L,(G) and M(G) denote Complement, Line graph, Jump graph, Splitting graph, Line splitting graph and Middle graph respectively. In this paper, we solve the graph equations L(G) =S(H), M(G) = S(H), L(G) = LS(H), M(G) =LS(H), J(G) = S(H), M(G) = S(H), J(G) = LS(H) and M(G) = LS(G).
B. Basavanagoud, Veena Mathad
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Graph Pattern Matching: From Intractable to Polynomial Time [PDF]

open access: yes, 2010
Graph pattern matching is typically defined in terms of sub-graph isomorphism, which makes it an np-complete problem. Moreover, it requires bijective functions, which are often too restrictive to characterize patterns in emerging applications. We propose
Li, Jianzhong   +5 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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