Results 81 to 90 of about 2,773,301 (295)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Mediate Dominating Graph of a Graph [PDF]
, 2011 The graphs considered here are finite and simple. Let G = (V,E) be a graph and let the vertices and edges of a graph G be called the elements of G. The undefined terminology and notations can be found in [2]
Basavanagoud, B., Sunilkumar M. Hosamani
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
A survey of two-dimensional graph layout techniques for information visualisation [PDF]
, 2012 Many algorithms for graph layout have been devised over the last 30 years spanning both the graph drawing and information visualisation communities. This article first reviews the advances made in the field of graph drawing that have then often been ...
Vickers, Paul, Gibson, Helen, Faith, Joe
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A Survey of the Algorithmic Properties of Simplicial, Upper Bound and Middle Graphs
Journal of Graph Algorithms and Applications, 2006 Three classes of graphs, simplicial, upper bound, and middle graphs, have been known for some time, but many of their algorithmic properties have not been published.
Grant Cheston, Tjoen Seng Jap
doaj +1 more source
Graph Pattern Matching: From Intractable to Polynomial Time [PDF]
, 2010 Graph pattern matching is typically defined in terms of sub-graph isomorphism, which makes it an np-complete problem. Moreover, it requires bijective functions, which are often too restrictive to characterize patterns in emerging applications. We propose
Li, Jianzhong +5 more
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Phases of tree-decorated Dynamical Triangulations in 3D
Journal of High Energy PhysicsThis work revisits the Euclidean Dynamical Triangulation (DT) approach to non-perturbative quantum gravity in three dimensions. Inspired by a recent combinatorial study [1] of a subclass of 3-sphere triangulations constructed from trees, called the ...
Timothy Budd, Dániel Németh
doaj +1 more source
A Method for Testing Graph Visualizations Using Games [PDF]
, 2007 We describe a system that enables us to perform exploratory empirical experiments with graph visualization techniques by incorporating them into games that can be played on an internet site, the Graph Games Website (http://www.cs.kent.ac.uk/projects ...
Bovey, John D. +3 more
core +1 more source