Results 111 to 120 of about 2,773,301 (295)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
On r-Dynamic Coloring of the Triple Star Graph Families
, 2018 In this paper we investigate the r-dynamic chromatic number of the central graph, middle graph, total graph and line graph of the triple star graph.
M. Venkatachalam (5758480) +1 more
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
PLoS ONEObjectiveCompared with those without such impairment, middle-aged and older adults with sensory impairment (SI) demonstrate a greater prevalence and severity of depressive symptoms, significantly affecting their mental health.
Mengzhen Qin +3 more
doaj +1 more source
Graph Drawing Techniques for Geographic Visualization [PDF]
, 2004 Geovisualizers often need to represent data that consists of items related together. Such data sets can be abstracted to a mathematical structure, the graph.
Rodgers, Peter
core
Minimizing the oriented diameter of a planar graph [PDF]
, 2009 We consider the problem of minimizing the diameter of an orientation of a planar graph. A result of Chvátal and Thomassen shows that for general graphs, it is NP-complete to decide whether a graph can be oriented so that its diameter is at most two.
Noble, SD +3 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Supporting Middle School Students’ Understanding of Time-Series Data With Graph Comparisons
Journal of Statistics and Data Science EducationAfter participating in an afterschool program where they used the Common Online Data Analysis Platform (CODAP) to study time-series data about infectious diseases, four middle school students were interviewed to determine how they understood features of ...
Jan Mokros, Jacob Sagrans, Pendred Noyce
doaj +1 more source
Bond Graph Based Stability Analysis of a Railway Traction System [PDF]
, 2005 This paper emphasises the interest of the Bond Graph approach for analysis and system design of heterogeneous and multi-field devices. In particular, the local stability analysis of non linear systems can be directly derived from the linearised Causal ...
Sareni, Bruno +3 more
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source