Results 61 to 70 of about 740,304 (299)
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
Middle Stone Age technological organisation from MIS 5 at Mertenhof Rockshelter, South Africa
Quaternary Science AdvancesLithic technological organisation within the southern Africa Early Middle Stone Age (∼315,000–80,000 years ago) has seen relatively little investigation owing to the subtly of technological change, frequent use of locally derived raw materials, and the ...
Corey A. O'Driscoll, Alex Mackay
doaj +1 more source
High-Calcium Limestone Deposits of Cumberland Valley, Pennsylvania [PDF]
, 1966 Author Institution: University of Minnesota, Minneapolis, MinnesotaHigh-calcium limestones occur in the upper part of the New Market Formation, of Lower Middle Ordovician age, in Franklin and Cumberland Counties, Pennsylvania.
Kraft, J. C. +2 more
core
Analysis of prehistoric brown earth paleosols under the podzol soils of Exmoor, UK [PDF]
, 2020 The deforestation of the upland landscapes in southwest Britain during prehistory is an established archaeological narrative, documenting human impacts on the environment and questioning the relationship of prehistoric societies to the upland landscapes ...
Bray, Lee +6 more
core +3 more sources
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Boyhood, initiation, homosexual behaviour and homosexuality in European Palaeolithic and Mesolithic [PDF]
, 2016 In this article, boyhood in European Pleistocene is decribed. After the introduction, it describes the terms "child" and "boy". In the section about the first people in Europe I have included the first people in Greece and Italy as well because most ...
Adrian van Mechelen
core +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
PLoS ONE, 2016 Heating stone to enhance its flaking qualities is among the multiple innovative adaptations introduced by early modern human groups in southern Africa, in particular during the Middle Stone Age Still Bay and Howiesons Poort traditions.
Anne Delagnes +8 more
doaj +1 more source
Fat residue and use-wear found on Acheulian biface and scraper associated with butchered elephant remains at the site of Revadim, Israel [PDF]
, 2015 The archaeological record indicates that elephants must have played a significant role in early human diet and culture during Palaeolithic times in the Old World.
A., Zupancich +5 more
core +3 more sources